SLC12A4 and TMEM102

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC12A4	TMEM102
Description		solute carrier family 12 member 4	transmembrane protein 102
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Membrane Synapse	Mitochondrion Plasma Membrane Cell Surface Membrane Protein-containing Complex
	Molecular Function	Protein Binding ATP Binding Symporter Activity Chloride:monoatomic Cation Symporter Activity Potassium:chloride Symporter Activity Protein Kinase Binding Transmembrane Transporter Activity Protein Serine/threonine Kinase Binding	Protein Binding
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Cell Volume Homeostasis Chemical Synaptic Transmission Chloride Ion Homeostasis Potassium Ion Homeostasis Transmembrane Transport Potassium Ion Transmembrane Transport Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Apoptotic Process Signal Transduction Positive Regulation Of T Cell Chemotaxis Response To Cytokine Positive Regulation Of Cell Adhesion Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of T Cell Migration
Pathways		Cation-coupled Chloride cotransporters
Drugs		Potassium chloride Bumetanide
Diseases
GWAS		Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)	Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278)
Interacting Genes		10 interacting genes: AP3M1 ATF7IP CNFN CYSRT1 KRTAP12-2 KRTAP19-2 MB21D2 MTNR1B TMEM102 ZNF655	2 interacting genes: SLC12A4 YWHAG
Entrez ID		6560	284114
HPRD ID		04987	08215
Ensembl ID		ENSG00000124067	ENSG00000181284
Uniprot IDs		B4DF30 Q9UP95	Q8N9M5
PDB IDs		6KKR 6KKT 6KKU 7AIP 7AIQ 7AIR 7TTH 7TTI
Enriched GO Terms of Interacting Partners?			Chloride Ion Homeostasis Potassium:chloride Symporter Activity Chloride:monoatomic Cation Symporter Activity Regulation Of T Cell Mediated Immune Response To Tumor Cell Positive Regulation Of Immune Response To Tumor Cell Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Protein Kinase C Inhibitor Activity Insulin-like Growth Factor Receptor Binding Negative Regulation Of Immune Response To Tumor Cell Negative Regulation Of T Cell Mediated Immune Response To Tumor Cell Phosphorylation-dependent Protein Binding
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