BMP8B and HPCA

Data Source: HiPPIP (Novel)

		BMP8B	HPCA
Name		bone morphogenetic protein 8b	hippocalcin
Structure		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Cytoplasm Cytosol Membrane Axon Dendrite Membrane Neuronal Cell Body Membrane Dendrite Cytoplasm Perikaryon Dendritic Spine Head Postsynapse Glutamatergic Synapse
	Molecular Function	Cytokine Activity Growth Factor Activity	Actin Binding Calcium Ion Binding Protein Binding Kinase Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Skeletal System Development Ossification Cell Differentiation BMP Signaling Pathway Developmental Process Negative Regulation Of Cell Differentiation Cartilage Development	Regulation Of Signal Transduction Calcium-mediated Signaling Inner Ear Development Retina Development In Camera-type Eye Cellular Response To Electrical Stimulus Cellular Response To Calcium Ion Positive Regulation Of Protein Targeting To Membrane Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Regulation Of Voltage-gated Calcium Channel Activity Response To Ketamine Response To L-glutamate Response To Aroclor 1254 Cellular Response To L-glutamate
GWAS		Haemorrhoidal disease ( 33888516 )	Daytime nap ( 33568662 )
Novel Interactors		3 novel interactors: HPCA NSD3 SLC2A1	12 novel interactors: APC BMP8B CSF3R DPYD E2F2 NDC80 NUDC RAE1 RUNX3 TMEM54 TNFRSF8 TUBA4A
Interacting Genes		1 interacting genes: BMP4	17 interacting genes: AP2B1 C1QTNF2 CKMT1A CKMT1B CREM DTX2 GATA5 IL36RN MLLT10 MYDGF NAIP NMT1 PRR35 SLC16A3 TEPSIN UQCRB VWC2
Entrez ID		656	3208
HPRD ID		03792	00811
Ensembl ID		ENSG00000116985	ENSG00000121905
Uniprot IDs		P34820	P84074
PDB IDs		Not available	5G4P 5G58 5M6C 7OWM
GO Terms Enriched among Interactors		Negative Regulation Of Metanephric Comma-shaped Body Morphogenesis Bud Dilation Involved In Lung Branching Apoptotic Process Involved In Endocardial Cushion Morphogenesis Negative Regulation Of Mesenchymal Cell Proliferation Involved In Ureter Development Intermediate Mesodermal Cell Differentiation Negative Regulation Of Metanephric S-shaped Body Morphogenesis Positive Regulation Of Cardiac Muscle Fiber Development Negative Regulation Of Glomerulus Development Kinase Binding Glucose Transporter Complex Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity Apoptotic Process Involved In Heart Morphogenesis Positive Regulation Of MiRNA Processing Negative Regulation Of Glomerular Mesangial Cell Proliferation Nephric Duct Formation Positive Regulation Of Primary MiRNA Processing Bronchus Development Positive Regulation Of Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Deltoid Tuberosity Development Tendon Cell Differentiation Epithelial Cell Proliferation Involved In Lung Morphogenesis Cardiac Jelly Development Negative Regulation Of Immature T Cell Proliferation Prostate Gland Morphogenesis Epithelial-mesenchymal Cell Signaling Negative Regulation Of Branching Involved In Ureteric Bud Morphogenesis Regulation Of Branching Involved In Lung Morphogenesis Telencephalon Regionalization Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Branching Involved In Prostate Gland Morphogenesis Glomerular Capillary Formation Pericyte Cell Differentiation Specification Of Animal Organ Position Trachea Development Regulation Of Prostatic Bud Formation Mesodermal Cell Fate Determination Prostatic Bud Formation Negative Regulation Of Immature T Cell Proliferation In Thymus Positive Regulation Of Branching Involved In Lung Morphogenesis Negative Regulation Of Cell Proliferation Involved In Kidney Development Lens Induction In Camera-type Eye Mammary Gland Formation Negative Regulation Of Prostatic Bud Formation Regulation Of Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Muscular Septum Morphogenesis Response To Aroclor 1254 Dendritic Spine Head Response To Ketamine Response To Thyroglobulin Triiodothyronine	Phosphocreatine Biosynthetic Process Creatine Kinase Activity