ACOT12 and MEOX1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ACOT12	MEOX1
Description		acyl-CoA thioesterase 12	mesenchyme homeobox 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Intercellular Bridge	Chromatin Nucleus Cytoplasm
	Molecular Function	Acetyl-CoA Hydrolase Activity Protein Binding ATP Binding Lipid Binding Hydrolase Activity Thiolester Hydrolase Activity Identical Protein Binding Carboxylic Ester Hydrolase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Acetyl-CoA Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process	Somite Specification Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development
Pathways		Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Fractures ( 30158200)
Interacting Genes		9 interacting genes: ACOT7 MEOX1 MEOX2 NAA10 NAA11 PAX5 PAX6 REL ZBTB8A	99 interacting genes: ACBD4 ACOT12 AIRIM ALOX5 ANAPC2 APP APPL1 ATG9A BANP BNIP2 BYSL C14orf119 C1orf50 CACNB3 CATSPERT CCDC102B CDC34 CIAO1 CIB3 CIMIP4 CKS1B CNOT11 CSNK2A1 CWF19L2 CYFIP1 DCX DNAAF19 DUSP3 EIF4A3 EIF4EBP1 EMD FMR1 GCC1 GEMIN2 GPANK1 GYS1 HMBOX1 HMGB3 HOMER3 HOXC8 HYCC2 INPP5J KANK2 KCTD7 L3MBTL2 LMNA MAPK9 MBD3 MCRS1 MEF2A MID1 MID2 MKRN3 MLX MORF4L1 MVP NAGK NDOR1 NEIL2 OSGIN1 PAGE3 PARVG PAX1 PAX3 PCP2 PDE4C PELI2 PIN1 PLCD4 PM20D2 POLR3GL PPM1F PRKAG1 PRKN QRICH1 RAD52 RANBP3 RBM41 RBM5 SDCBP SEC14L4 SOX10 SPAG8 SPIC SYT17 TCEANC TCP11L1 TRAPPC2L TRIM41 TRIML2 TRIP10 TXLNA TXNL4B UBE2R2 UBXN2B UBXN7 UNC45A ZCCHC10 ZNF410
Entrez ID		134526	4222
HPRD ID		16680	02537
Ensembl ID		ENSG00000172497	ENSG00000005102
Uniprot IDs		Q8WYK0	P50221
PDB IDs		3B7K 4MOB 4MOC
Enriched GO Terms of Interacting Partners?		Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Protein N-terminal-serine Acetyltransferase Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Somite Specification RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity HMG Box Domain Binding N-terminal Protein Amino Acid Acetylation Segment Specification Somite Development Sequence-specific DNA Binding Chromatin Protein Acetylation Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Embryonic Pattern Specification Regulation Of Transcription By RNA Polymerase II Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Long-chain Fatty-acyl-CoA Catabolic Process Palmitic Acid Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Cerebral Cortex Development Pattern Specification Process Positive Regulation Of RNA Metabolic Process Sclerotome Development Habenula Development Pallium Development Medium-chain Fatty Acid Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Embryonic Organ Morphogenesis Regulation Of Asymmetric Cell Division Oligodendrocyte Cell Fate Specification NF-kappaB Complex Long-chain Fatty Acyl-CoA Binding Medium-chain Fatty-acyl-CoA Metabolic Process Nucleus Forebrain Dorsal/ventral Pattern Formation Regulation Of Centromeric Sister Chromatid Cohesion Negative Regulation Of Sister Chromatid Cohesion	Protein Binding Cytosol Nucleoplasm Cytoplasm Growth Cone Filopodium Spindle Pole Centrosome Translation Repressor Activity Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Identical Protein Binding Perinuclear Region Of Cytoplasm Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Translation At Postsynapse
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