SLC1A2 and AJUBA

Number of citations of the paper that reports this interaction (PMID 11860269)
9

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		SLC1A2	AJUBA
Gene Name		solute carrier family 1 (glial high affinity glutamate transporter), member 2	ajuba LIM protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane Axolemma	Cytoplasmic MRNA Processing Body Nucleus Transcription Factor Complex Microtubule Organizing Center Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Lamellipodium
	Molecular Function	L-glutamate Transmembrane Transporter Activity Protein Binding Glutamate:sodium Symporter Activity Sodium:dicarboxylate Symporter Activity	Chromatin Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding Alpha-catenin Binding Actin Filament Binding
	Biological Process	Ion Transport Synaptic Transmission Visual Behavior Response To Wounding Multicellular Organismal Aging Telencephalon Development Adult Behavior Cellular Response To Extracellular Stimulus Multicellular Organism Growth Response To Drug Response To Amino Acid Positive Regulation Of Glucose Import L-glutamate Import Transmembrane Transport D-aspartate Import L-glutamate Transmembrane Transport	G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Cell Cycle Response To Hypoxia Transcription, DNA-templated Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Lamellipodium Assembly Regulation Of Cell Migration Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Protein Complex Assembly Negative Regulation Of Kinase Activity Cellular Protein Localization Gene Silencing By MiRNA Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Hippo Signaling Regulation Of GTPase Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAP Kinase Activity Glycerophospholipid Biosynthetic Process Focal Adhesion Assembly Regulation Of Cellular Response To Hypoxia Positive Regulation Of Gene Silencing By MiRNA
Pathways		Astrocytic Glutamate-Glutamine Uptake And Metabolism Neurotransmitter uptake and Metabolism In Glial Cells Transport of inorganic cations/anions and amino acids/oligopeptides SLC-mediated transmembrane transport Transmission across Chemical Synapses	G2/M Transition Mitotic G2-G2/M phases Regulation of PLK1 Activity at G2/M Transition Cell Cycle, Mitotic
Drugs		L-Glutamic Acid
Diseases
GWAS		Essential tremor ( 22764253)	Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328)
Protein-Protein Interactions		2 interactors: AJUBA GRB2	10 interactors: ACTA1 AURKAIP1 AURKB BCAR1 CTNNA1 GFI1B GRB2 LATS2 LCK SLC1A2
Entrez ID		6506	84962
HPRD ID		02625	16426
Ensembl ID		ENSG00000110436	ENSG00000129474
Uniprot IDs		A2A2U1 P43004	Q96IF1
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Complex Assembly Positive Regulation Of Cellular Component Biogenesis Regulation Of Protein Complex Assembly Positive Regulation Of Gene Silencing By MiRNA Regulation Of Cellular Response To Hypoxia Negative Regulation Of Hippo Signaling Morphogenesis Of An Epithelium Wound Healing Regulation Of Hippo Signaling Regulation Of MAPK Cascade Tissue Morphogenesis Regulation Of Gene Silencing By MiRNA Branching Involved In Labyrinthine Layer Morphogenesis Wound Healing, Spreading Of Epidermal Cells Response To Wounding Cell Migration Cell Motility Regulation Of Gene Silencing Labyrinthine Layer Morphogenesis Epithelium Development Negative Regulation Of Signal Transduction Response To Abiotic Stimulus Embryonic Placenta Morphogenesis Cell Projection Organization Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Negative Regulation Of Signaling Focal Adhesion Assembly Locomotion Positive Regulation Of Signal Transduction Gene Silencing By MiRNA Wound Healing, Spreading Of Cells Regulation Of Phosphorylation Posttranscriptional Gene Silencing Receptor Internalization Adherens Junction Assembly Lamellipodium Assembly Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Negative Regulation Of ERBB Signaling Pathway Movement Of Cell Or Subcellular Component Lamellipodium Organization Cell-substrate Junction Assembly Labyrinthine Layer Development Cellular Response To Ionizing Radiation Morphogenesis Of An Epithelial Sheet Gene Silencing By RNA Tissue Development Regulation Of Intracellular Signal Transduction Regulation Of Epidermal Growth Factor Receptor Signaling Pathway T Cell Costimulation	Aging Response To Hormone Response To Wounding Response To Organonitrogen Compound Response To Organic Substance Cellular Response To Organonitrogen Compound Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Abiotic Stimulus Organ Development Organelle Organization Platelet Activation Cellular Response To Hormone Stimulus Multicellular Organismal Development Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway B Cell Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Actin Filament Organization Developmental Process Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Enzyme Linked Receptor Protein Signaling Pathway System Development Regulation Of Organelle Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway T Cell Costimulation Response To External Stimulus Negative Regulation Of Cell Division Cellular Response To Organic Substance Blood Coagulation Cell Division Regulation Of Cellular Component Organization Hemostasis Response To Radiation Negative Regulation Of Cell Cycle Response To Peptide Hormone Cytoskeleton Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Skeletal Muscle Fiber Adaptation Negative Regulation Of Integrin-mediated Signaling Pathway Cellular Response To Stimulus Response To Peptide T Cell Receptor Signaling Pathway Anatomical Structure Development Protein Heterooligomerization Histone H3-S28 Phosphorylation D-aspartate Import
Tagcloud ?		accumbens adulthood buf buffalo comt d53 d66 d74 disrupts erbb4 grid2 housed lfp lfps mpfc nac ncam1 neurophysiological nrg1 ppi prefrontal prepulse reared rearing reln sh socially startle sz	belongs carp cdna connect contained cytoplasm cytoskeleton entire extracellular frame gcrv grass hybrid immediately immunoprecipitation inducible ip jx01 lim location matrix ns26 orf overlap polypeptide reading responding sub
Tagcloud (Difference) ?		accumbens adulthood buf buffalo comt d53 d66 d74 disrupts erbb4 grid2 housed lfp lfps mpfc nac ncam1 neurophysiological nrg1 ppi prefrontal prepulse reared rearing reln sh socially startle sz	belongs carp cdna connect contained cytoplasm cytoskeleton entire extracellular frame gcrv grass hybrid immediately immunoprecipitation inducible ip jx01 lim location matrix ns26 orf overlap polypeptide reading responding sub
Tagcloud (Intersection) ?