PAPOLG and NFYA

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		PAPOLG	NFYA
Gene Name		poly(A) polymerase gamma	nuclear transcription factor Y, alpha
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane	Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex
	Molecular Function	RNA Binding Polynucleotide Adenylyltransferase Activity ATP Binding Metal Ion Binding	Core Promoter Sequence-specific DNA Binding Transcription Cofactor Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding
	Biological Process	MRNA Polyadenylation RNA Polyadenylation	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Rhythmic Process Regulation Of Stem Cell Maintenance Positive Regulation Of Stem Cell Proliferation
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins ATF4 activates genes ATF6-alpha activates chaperone genes Regulation of cholesterol biosynthesis by SREBP (SREBF) Activation of gene expression by SREBF (SREBP) Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) PERK regulates gene expression ATF6-alpha activates chaperones Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS		Crohn's disease ( 22412388)
Protein-Protein Interactions		3 interactors: LZTR1 NFYA PCBD1	37 interactors: APP APPBP2 ATF6 ATF6B BRCA1 CCNA2 CDC25A CDK2 CEBPA CSNK2A1 ELF1 GTF2A1 HMGA1 JUN KPNB1 LUC7L2 NFYB NFYC NR5A1 PAPOLG POGZ POU2F1 PWP1 SP1 SPI1 SREBF2 SRF SRSF1 TAF11 TAF12 TAF6 TP53 USF1 USF2 ZHX1 ZHX2 ZHX3
Entrez ID		64895	4800
HPRD ID		11420	01793
Ensembl ID		ENSG00000115421
Uniprot IDs		Q59G05 Q9BWT3	P23511
PDB IDs		4LT6	4AWL
Enriched GO Terms of Interacting Partners?		Tetrahydrobiopterin Biosynthetic Process L-phenylalanine Catabolic Process L-phenylalanine Metabolic Process Regulation Of Protein Homodimerization Activity Regulation Of Stem Cell Maintenance Pteridine-containing Compound Biosynthetic Process Aromatic Amino Acid Family Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Pteridine-containing Compound Metabolic Process Protein Homotetramerization Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Stem Cell Proliferation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Protein Tetramerization Regulation Of Stem Cell Proliferation Cellular Amino Acid Catabolic Process Protein Heterooligomerization Regulation Of Protein Binding Coenzyme Biosynthetic Process	Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription From RNA Polymerase II Promoter Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Viral Process Cellular Metabolic Process Positive Regulation Of Transcription By Glucose Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Positive Regulation By Host Of Viral Transcription Negative Regulation Of Nucleic Acid-templated Transcription Metabolic Process Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Initiation Late Viral Transcription Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Cellular Response To Nutrient Levels Regulation Of Cell Cycle
Tagcloud ?			anomalies behind bioinformatics cart ctf dependence depicting ebpbeta elaborate govern instance intron likewise modify nutshell oprk1 pdyn pdyns pharmaceutical prodynorphin prompting regimes retrieve snps tbp usf usf2 vdr vulnerability
Tagcloud (Difference) ?			anomalies behind bioinformatics cart ctf dependence depicting ebpbeta elaborate govern instance intron likewise modify nutshell oprk1 pdyn pdyns pharmaceutical prodynorphin prompting regimes retrieve snps tbp usf usf2 vdr vulnerability
Tagcloud (Intersection) ?