NFYA and USF2

Number of citations of the paper that reports this interaction (PMID 12791656)
18

Data Source:
HPRD (in vitro, in vivo)

		NFYA	USF2
Gene Name		nuclear transcription factor Y, alpha	upstream transcription factor 2, c-fos interacting
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex	Nucleus Nucleoplasm
	Molecular Function	Core Promoter Sequence-specific DNA Binding Transcription Cofactor Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Double-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Rhythmic Process Regulation Of Stem Cell Maintenance Positive Regulation Of Stem Cell Proliferation	Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Transcription From RNA Polymerase II Promoter Lactation Late Viral Transcription Positive Regulation Of Transcription From RNA Polymerase II Promoter Lipid Homeostasis
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins ATF4 activates genes ATF6-alpha activates chaperone genes Regulation of cholesterol biosynthesis by SREBP (SREBF) Activation of gene expression by SREBF (SREBP) Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) PERK regulates gene expression ATF6-alpha activates chaperones Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		37 interactors: APP APPBP2 ATF6 ATF6B BRCA1 CCNA2 CDC25A CDK2 CEBPA CSNK2A1 ELF1 GTF2A1 HMGA1 JUN KPNB1 LUC7L2 NFYB NFYC NR5A1 PAPOLG POGZ POU2F1 PWP1 SP1 SPI1 SREBF2 SRF SRSF1 TAF11 TAF12 TAF6 TP53 USF1 USF2 ZHX1 ZHX2 ZHX3	11 interactors: BRCA1 EP300 FOS LZTS2 MAF NFYA PPARGC1A PPRC1 RELA TEAD2 USF1
Entrez ID		4800	7392
HPRD ID		01793	02668
Ensembl ID			ENSG00000105698
Uniprot IDs		P23511	Q15853
PDB IDs		4AWL
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription From RNA Polymerase II Promoter Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Viral Process Cellular Metabolic Process Positive Regulation Of Transcription By Glucose Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Positive Regulation By Host Of Viral Transcription Negative Regulation Of Nucleic Acid-templated Transcription Metabolic Process Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Initiation Late Viral Transcription Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Cellular Response To Nutrient Levels Regulation Of Cell Cycle	Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Transcription, DNA-templated Positive Regulation Of Metabolic Process RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Gene Expression Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Response To Hormone Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Abiotic Stimulus Nitrogen Compound Metabolic Process Cellular Response To Tumor Necrosis Factor Response To Organonitrogen Compound Response To Lipid Response To Tumor Necrosis Factor Response To Organic Cyclic Compound Positive Regulation Of Histone Acetylation Response To Radiation Positive Regulation Of Peptidyl-lysine Acetylation Response To Extracellular Stimulus Positive Regulation Of Protein Acetylation Response To Steroid Hormone Regulation Of Metabolic Process Cellular Response To Organic Substance Response To Temperature Stimulus Intracellular Receptor Signaling Pathway Cellular Response To Oxidative Stress Cellular Response To Hormone Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Androgen Receptor Signaling Pathway
Tagcloud ?		anomalies behind bioinformatics cart ctf dependence depicting ebpbeta elaborate govern instance intron likewise modify nutshell oprk1 pdyn pdyns pharmaceutical prodynorphin prompting regimes retrieve snps tbp usf usf2 vdr vulnerability	anomalies behind bioinformatics cart ctf dependence depicting ebpbeta elaborate govern instance intron likewise modify nfya nutshell oprk1 pdyn pdyns pharmaceutical prodynorphin prompting regimes retrieve snps tbp vdr vulnerability
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		anomalies behind bioinformatics cart ctf dependence depicting ebpbeta elaborate govern instance intron likewise modify nfya nutshell oprk1 pdyn pdyns pharmaceutical prodynorphin prompting regimes retrieve snps tbp usf usf2 vdr vulnerability