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PAPOLG

Description poly(A) polymerase gamma
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytosol
  • Membrane
  • Nuclear Body
Molecular Function
  • Nucleotide Binding
  • RNA Binding
  • ATP Binding
  • Transferase Activity
  • Nucleotidyltransferase Activity
  • Metal Ion Binding
  • Poly(A) RNA Polymerase Activity
Biological Process
  • MRNA Processing
  • RNA 3'-end Processing
Pathways
  • Nuclear RNA decay
Drugs
Diseases
GWAS
  • Acne (severe) ( 24927181)
  • Asthma ( 32296059)
  • Composite immunoglobulin trait (IgA/IgM) ( 28628107)
  • Crohn's disease ( 22412388)
  • Erectile dysfunction ( 30583798)
  • Metabolite levels ( 23823483)
  • Multiple sclerosis ( 31604244)
  • Systemic lupus erythematosus ( 28714469)
Interacting Genes 3 interacting genes: LZTR1 NFYA PCBD1
Entrez ID 64895
HPRD ID 11420
Ensembl ID ENSG00000115421
Uniprot IDs Q9BWT3
PDB IDs 4LT6
Enriched GO Terms of Interacting Partners?
  • 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity
  • Tyrosine Biosynthetic Process
  • Phenylalanine 4-monooxygenase Activity
  • Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine
  • CCAAT-binding Factor Complex
  • Tetrahydrobiopterin Biosynthetic Process
  • Tetrahydrobiopterin Metabolic Process
  • Pteridine-containing Compound Biosynthetic Process
  • Tyrosine Metabolic Process
  • Negative Regulation Of Ras Protein Signal Transduction
  • Diol Metabolic Process
  • Pteridine-containing Compound Metabolic Process
  • Protein-DNA Complex
  • Aromatic Amino Acid Metabolic Process
  • Regulation Of Ras Protein Signal Transduction
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