APBA3

Gene Name		amyloid beta (A4) precursor protein-binding, family A, member 3
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Gene Ontology Annotations	Cellular Component	Perinuclear Region Of Cytoplasm
	Molecular Function	Beta-amyloid Binding Enzyme Inhibitor Activity Protein Binding Enzyme Binding
	Biological Process	In Utero Embryonic Development Synaptic Transmission Regulation Of Gene Expression Protein Transport Negative Regulation Of Catalytic Activity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: APP AZI2 BCR EGFR TANK TBKBP1
Entrez ID		9546
HPRD ID		05038
Ensembl ID		ENSG00000011132
Uniprot IDs		O96018
PDB IDs		2YT7 2YT8
Enriched GO Terms of Interacting Partners?		Innate Immune Response Immune System Process I-kappaB Kinase/NF-kappaB Signaling Immune Response Defense Response Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Regulation Of ERBB Signaling Pathway Tumor Necrosis Factor Production Alkanesulfonate Metabolic Process Cell Activation Neuromuscular Process Synaptic Growth At Neuromuscular Junction Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Intracellular Signal Transduction Brain Development Head Development Interferon-alpha Production Collateral Sprouting In Absence Of Injury Regulation Of Immune Response Interleukin-6 Production Activation Of Phospholipase A2 Activity Regulation Of Cell Cycle Regulation Of Peptidyl-tyrosine Phosphorylation Protein Autophosphorylation Positive Regulation Of Phospholipase A2 Activity Collateral Sprouting Axon Midline Choice Point Recognition Dendritic Cell Proliferation Central Nervous System Development Response To Cobalamin Response To UV-A Negative Regulation Of Neutrophil Degranulation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Hydrolase Activity Response To Hydroxyisoflavone Regulation Of Neutrophil Degranulation Negative Regulation Of Neutrophil Activation Axon Choice Point Recognition Response To Stimulus Learning Or Memory Positive Regulation Of Superoxide Anion Generation Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Inflammatory Response Peptidyl-tyrosine Phosphorylation Neurological System Process Positive Regulation Of Cell Cycle Cognition Cell Adhesion
Tagcloud ?		a4 additive aging amyloid apbb1 aplp1 apolipoprotein c57bl clues dysregulation elusive fe65 hippocampal hypertension hypertensive impairments m1 manifestation maze mint3 mo muscarinic object precursor predisposes secretases signature tauopathy wk