VSIR and SLC35B1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VSIR	SLC35B1
Description		V-set immunoregulatory receptor	solute carrier family 35 member B1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Enzyme Binding Identical Protein Binding Endopeptidase Activator Activity	UDP-galactose Transmembrane Transporter Activity UDP-glucose Transmembrane Transporter Activity ATP:ADP Antiporter Activity Protein Binding Antiporter Activity
	Biological Process	Positive Regulation Of Gene Expression Positive Regulation Of Endopeptidase Activity Positive Regulation Of Cell Migration Zymogen Activation Negative Regulation Of Type II Interferon Production Negative Regulation Of Interleukin-10 Production Negative Regulation Of Interleukin-17 Production Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Regulatory T Cell Differentiation Negative Regulation Of Alpha-beta T Cell Activation Regulation Of Immune Response Positive Regulation Of Collagen Catabolic Process Negative Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Negative Regulation Of CD8-positive, Alpha-beta T Cell Proliferation	UDP-glucose Transmembrane Transport ADP Transport ATP Transport Transmembrane Transport UDP-galactose Transmembrane Transport
Pathways
Drugs
Diseases
GWAS
Interacting Genes		27 interacting genes: APOD ASGR1 ATP6V0C BMP10 C14orf180 CCL4L2 CLEC7A CLRN2 CNIH3 DOLK MS4A13 PLPP6 PLPPR2 PLSCR1 SLC35B1 SLC35B4 SMAD3 SMCO4 TMEM100 TMEM14C TMEM218 TMEM229B TMEM97 TNF TSPAN2 TSPO2 VAMP3	20 interacting genes: APP AQP6 ARL13B BNIP3 CCDC107 CD74 CD79A CREB3L1 DRD2 FKBP8 FXYD3 FZD5 FZD7 GPR152 HRH1 MFF PDZK1IP1 PTPN5 VAPA VSIR
Entrez ID		64115	10237
HPRD ID		15160	10237
Ensembl ID		ENSG00000107738	ENSG00000121073
Uniprot IDs		Q9H7M9	P78383
PDB IDs		6MVL 6OIL 6U6V 8TBQ
Enriched GO Terms of Interacting Partners?		Membrane Positive Regulation Of Neutrophil Activation Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process Cholesterol Binding Plasma Membrane Regulation Of Wound Healing Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Interleukin-1 Beta Production Regulation Of Neutrophil Activation Nucleotide-sugar Transmembrane Transport Pyrimidine Nucleotide-sugar Transmembrane Transport Regulation Of Response To Wounding Regulation Of Nitric Oxide Metabolic Process Positive Regulation Of Interleukin-1 Production Phosphatidate Phosphatase Activity Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Regulation Of Calcium-mediated Signaling Positive Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Chemokine Production Regulation Of Interleukin-1 Beta Production Negative Regulation Of Lipoprotein Lipid Oxidation Negative Regulation Of MiRNA Transcription Positive Regulation Of Cartilage Development Regulation Of Interleukin-1 Production Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Activin Receptor Signaling Pathway Organophosphate Ester Transport Negative Regulation Of Bile Acid Secretion Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Regulation Of Calcineurin-mediated Signaling Regulation Of Calcineurin-NFAT Signaling Cascade Response To Gram-negative Bacterium Negative Regulation Of Branching Involved In Lung Morphogenesis Positive Regulation Of Cytokine Production Involved In Inflammatory Response Dolichol Kinase Activity Detection Of Yeast Detection Of Molecule Of Fungal Origin Phospholipid Dephosphorylation UDP-xylose Transmembrane Transport UDP-xylose Transmembrane Transporter Activity 5-aminolevulinic Acid Import Across Plasma Membrane 5-aminolevulinic Acid Transmembrane Transporter Activity Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Negative Regulation Of Cardiac Muscle Hypertrophy	Membrane Plasma Membrane Visual Learning Regulation Of Autophagy Of Mitochondrion Interneuron Migration From The Subpallium To The Cortex Visual Behavior Signal Transduction Response To Histamine G Protein-coupled Receptor Activity Identical Protein Binding Negative Regulation Of B Cell Apoptotic Process Mitochondrial Envelope Endoplasmic Reticulum Membrane Wnt Receptor Activity Dendrite Protein Trimerization Associative Learning G Protein-coupled Receptor Signaling Pathway Regulation Of Neurotransmitter Uptake Regulation Of B Cell Apoptotic Process Cell Surface Receptor Signaling Pathway Positive Regulation Of Mitochondrial Fission Insulin Receptor Binding Positive Regulation Of Long-term Synaptic Potentiation Regulation Of Type II Interferon Production Memory Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Phosphorus Metabolic Process Leukocyte Activation Positive Regulation Of Receptor Internalization Wnt-protein Binding Regulation Of Mitochondrial Fission Non-motile Cilium Perikaryon Positive Regulation Of Immune System Process Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Positive Regulation Of Cell Activation Regulation Of Immune Response Regulation Of Response To Calcium Ion Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Tumor Necrosis Factor Production Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Small Molecule Metabolic Process Learning Cell Activation Frizzled Binding
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