SLC35B1 and FZD7

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		SLC35B1	FZD7
Description		solute carrier family 35 member B1	frizzled class receptor 7
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Intracellular Membrane-bounded Organelle	Endosome Plasma Membrane Endosome Membrane Membrane Recycling Endosome Membrane
	Molecular Function	UDP-galactose Transmembrane Transporter Activity UDP-glucose Transmembrane Transporter Activity ATP:ADP Antiporter Activity Protein Binding Antiporter Activity	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Frizzled Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Wnt-protein Binding PDZ Domain Binding Wnt Receptor Activity
	Biological Process	UDP-glucose Transmembrane Transport ADP Transport ATP Transport Transmembrane Transport UDP-galactose Transmembrane Transport	Regulation Of DNA-templated Transcription Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Cell-substrate Adhesion Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration Wnt Signaling Pathway Stem Cell Population Maintenance Neuron Differentiation T Cell Differentiation In Thymus Substrate Adhesion-dependent Cell Spreading Non-canonical Wnt Signaling Pathway Positive Regulation Of Phosphorylation Negative Regulation Of Ectodermal Cell Fate Specification Positive Regulation Of MAPK Cascade Positive Regulation Of DNA-templated Transcription Positive Regulation Of JNK Cascade Somatic Stem Cell Division Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Canonical Wnt Signaling Pathway Wnt Signaling Pathway, Planar Cell Polarity Pathway Mesenchymal To Epithelial Transition Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Retinoic Acid Negative Regulation Of Cardiac Muscle Cell Differentiation
Pathways			Class B/2 (Secretin family receptors) PCP/CE pathway PCP/CE pathway Asymmetric localization of PCP proteins WNT5:FZD7-mediated leishmania damping WNT5:FZD7-mediated leishmania damping
Drugs
Diseases
GWAS			Age at first sexual intercourse ( 34211149) Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Blond vs. brown/black hair color ( 30531825) Heel bone mineral density ( 28869591 30598549) Metabolite levels ( 23823483) Risk-taking tendency (4-domain principal component model) ( 30643258) Total body bone mineral density ( 29304378)
Interacting Genes		20 interacting genes: APP AQP6 ARL13B BNIP3 CCDC107 CD74 CD79A CREB3L1 DRD2 FKBP8 FXYD3 FZD5 FZD7 GPR152 HRH1 MFF PDZK1IP1 PTPN5 VAPA VSIR	30 interacting genes: ADCY1 AIG1 AQP9 BCL2L13 CCDC88C CLN8 CLPTM1 DLG1 DLG2 DLG4 DVL1 FFAR2 GNAS HPCAL1 LEUTX MAGI3 MGST1 NCALD NCS1 PDAP1 PRNP PSME3IP1 SGTA SGTB SLC30A4 SLC35B1 TMEM237 UBQLN1 UBQLN2 UBQLN4
Entrez ID		10237	8324
HPRD ID		10237	04560
Ensembl ID		ENSG00000121073	ENSG00000155760
Uniprot IDs		P78383	O75084
PDB IDs			4Z33 5T44 5URV 5WBS 6NE2 6NE4 6O3A 6O3B 8QEO 8YY8 9EPO 9EW2
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Visual Learning Regulation Of Autophagy Of Mitochondrion Interneuron Migration From The Subpallium To The Cortex Visual Behavior Signal Transduction Response To Histamine G Protein-coupled Receptor Activity Identical Protein Binding Negative Regulation Of B Cell Apoptotic Process Mitochondrial Envelope Endoplasmic Reticulum Membrane Wnt Receptor Activity Dendrite Protein Trimerization Associative Learning G Protein-coupled Receptor Signaling Pathway Regulation Of Neurotransmitter Uptake Regulation Of B Cell Apoptotic Process Cell Surface Receptor Signaling Pathway Positive Regulation Of Mitochondrial Fission Insulin Receptor Binding Positive Regulation Of Long-term Synaptic Potentiation Regulation Of Type II Interferon Production Memory Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Phosphorus Metabolic Process Leukocyte Activation Positive Regulation Of Receptor Internalization Wnt-protein Binding Regulation Of Mitochondrial Fission Non-motile Cilium Perikaryon Positive Regulation Of Immune System Process Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Positive Regulation Of Cell Activation Regulation Of Immune Response Regulation Of Response To Calcium Ion Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Tumor Necrosis Factor Production Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Long-term Synaptic Potentiation Positive Regulation Of Small Molecule Metabolic Process Learning Cell Activation Frizzled Binding	Postsynaptic Density GMP Kinase Activity Ionotropic Glutamate Receptor Binding Regulation Of Proteolysis GDP Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Receptor Clustering TRC Complex Positive Regulation Of ERAD Pathway Membrane Ribonucleoside Diphosphate Metabolic Process Regulation Of ERAD Pathway Nucleoside Diphosphate Metabolic Process GMP Metabolic Process Dendritic Spine Organization Kinase Binding Frizzled Binding Postsynaptic Density Membrane Polyubiquitin Modification-dependent Protein Binding Regulation Of Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Response To Endoplasmic Reticulum Stress Neuron Projection Organization D1 Dopamine Receptor Binding Postsynapse Organization Plasma Membrane Positive Regulation Of Neuron Projection Arborization Receptor Localization To Synapse Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Establishment Or Maintenance Of Apical/basal Cell Polarity Negative Regulation Of Proteolysis Social Behavior Purine Ribonucleotide Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Protein Localization To Synapse Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Ribonucleotide Metabolic Process Establishment Or Maintenance Of Cell Polarity Juxtaparanode Region Of Axon Cytoplasmic Microtubule Organization Ribose Phosphate Metabolic Process Cognition Cellular Response To Metal Ion Immunological Synapse Formation Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Cellular Response To Potassium Ion Response To Metal Ion Nucleoside Monophosphate Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?