PARVG and CFAP53

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PARVG	CFAP53
Description		parvin gamma	cilia and flagella associated protein 53
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Actin Cytoskeleton Membrane Anchoring Junction	Spindle Pole Manchette Extracellular Region Cytoplasm Centriole Cytoskeleton Axonemal Microtubule Cilium Axoneme Motile Cilium Centriolar Satellite Ciliary Transition Zone Sperm Flagellum Cell Projection Polymeric Cytoskeletal Fiber Axonemal A Tubule Inner Sheath
	Molecular Function	Actin Binding Protein Binding	Protein Binding
	Biological Process	Cell Adhesion Cell-matrix Adhesion Cell Projection Assembly Actin Cytoskeleton Organization Substrate Adhesion-dependent Cell Spreading Establishment Or Maintenance Of Cell Polarity Regulating Cell Shape	Cilium Movement Spermatogenesis Determination Of Left/right Symmetry Cell Projection Organization Cell Differentiation Flagellated Sperm Motility Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Sperm Flagellum Assembly Manchette Assembly
Pathways
Drugs
Diseases
GWAS		Fasting glucose ( 33381925) Metabolite levels ( 23823483) Survival in colon cancer ( 25866641)
Interacting Genes		33 interacting genes: ALX4 ANTKMT APP CDHR3 CDSN CFAP53 CSF3 DDIT4L FOSL1 GADD45A HOMEZ ILK KCTD7 KLHL32 LHX3 LNX2 MEOX1 MEOX2 NBPF22P NBPF6 NDEL1 PDLIM7 POLR2G POU6F2 REL SERTAD2 TLE5 TRIB2 TRIM54 TSGA10IP USHBP1 ZNF426 ZNF677	29 interacting genes: APP CBY1 CCDC57 CCDC85B CCHCR1 CCNC CEP70 CWF19L2 DRC4 GRIPAP1 HIP1 HMG20A KRT31 KRT34 LDOC1 LENG8 MYOG PARVG PIBF1 PNMA1 RABEP1 SH2D4A TBC1D21 TEX11 TNIP1 TRIM23 TRIM54 TXLNA TXLNB
Entrez ID		64098	220136
HPRD ID		16285	09958
Ensembl ID		ENSG00000138964	ENSG00000172361
Uniprot IDs		Q9HBI0	Q96M91
PDB IDs			7UNG 8J07
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Somite Specification DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin HMG Box Domain Binding Positive Regulation Of RNA Metabolic Process Segment Specification Somite Development RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process	Cytoskeleton
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