PILRB

Description		paired immunoglobin like type 2 receptor beta
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GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Protein Binding MHC Class I Protein Binding
	Biological Process	Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Brain morphology (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Hemoglobin ( 32888494) Monocyte count ( 32888494) Post bronchodilator FEV1 ( 26634245) Subcortical volume (MOSTest) ( 32665545)
Novel Interacting Genes		1 novel interacting genes: TNF
Interacting Genes		6 interacting genes: ABHD16A BRCA1 LYN PTPN11 PTPN6 SAMSN1
Entrez ID		29990
HPRD ID		08382
Ensembl ID		ENSG00000121716
Uniprot IDs		Q9UKJ0
PDB IDs		4NFC 4NFD
Enriched GO Terms of Interacting Partners?		Regulation Of Neutrophil Activation Negative Regulation Of Immune System Process Negative Regulation Of Lymphocyte Activation Negative Regulation Of Leukocyte Activation T Cell Costimulation Regulation Of Cell Adhesion Mediated By Integrin Phosphotyrosine Residue Binding Negative Regulation Of Cell Activation Regulation Of Cell Activation Myeloid Cell Differentiation Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Cell Cycle Process Negative Regulation Of Neutrophil Activation Protein-containing Complex Regulation Of Cytokine Production Negative Regulation Of Lymphocyte Proliferation Positive Regulation Of Cell-cell Adhesion Negative Regulation Of Mononuclear Cell Proliferation Negative Regulation Of Cell Cycle DNA Damage Checkpoint Signaling Phosphorylation-dependent Protein Binding Negative Regulation Of Leukocyte Proliferation Positive Regulation Of Cell Activation Regulation Of Leukocyte Cell-cell Adhesion Immune Effector Process Negative Regulation Of B Cell Receptor Signaling Pathway Non-membrane Spanning Protein Tyrosine Phosphatase Activity Inflammatory Response To Wounding Neutrophil Activation Involved In Immune Response Regulation Of Immune Response Cytokine-mediated Signaling Pathway Regulation Of Cell Cycle Phase Transition Regulation Of Innate Immune Response Myeloid Leukocyte Activation Regulation Of Intracellular Signal Transduction Regulation Of B Cell Activation Regulation Of Cell Cycle Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Mitotic Cell Cycle Signal Transduction In Response To DNA Damage Regulation Of Mast Cell Activation Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion Leukocyte Activation Involved In Immune Response Positive Regulation Of Cytokine Production Regulation Of Lymphocyte Activation Cell Activation Involved In Immune Response Negative Regulation Of Multicellular Organismal Process Peptidyl-tyrosine Dephosphorylation
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