PRDM16 and INADL

Number of citations of the paper that reports this interaction (PMID 16637659)
18

Data Source:
HPRD (in vitro)

		PRDM16	INADL
Gene Name		PR domain containing 16	InaD-like (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcriptional Repressor Complex	Plasma Membrane Tight Junction Apical Plasma Membrane Protein Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Transcription Coactivator Activity Protein Binding Sequence-specific DNA Binding SMAD Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Neurogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Granulocyte Differentiation Somatic Stem Cell Maintenance Regulation Of Cellular Respiration Tongue Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated White Fat Cell Differentiation Brown Fat Cell Differentiation Palate Development	Cell Junction Assembly Intracellular Signal Transduction Cell-cell Junction Organization Tight Junction Assembly
Pathways			Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS		Migraine ( 21666692) Response to statin therapy ( 20339536)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		1 interactors: INADL	28 interactors: ASIC3 BAI1 CACNG2 CLDN1 CNKSR2 CRB3 CRIPT DDX18 GLS2 GRIN2A GRIN2B GRIN2C GRIN2D KCNA4 KCNJ10 KCNJ15 KCNJ2 KIF1B MAPK12 MPP5 NLGN2 NRXN2 PARD3 PAX6 PRDM16 SCN4A SCN5A TJP3
Entrez ID		63976	10207
HPRD ID		16122	04434
Ensembl ID		ENSG00000142611	ENSG00000132849
Uniprot IDs		D6RDW0 Q9HAZ2	Q8NI35
PDB IDs			1VF6 2D92 2DAZ 2DB5 2DLU 2DM8 2DMZ 2EHR
Enriched GO Terms of Interacting Partners?		Tight Junction Assembly Apical Junction Assembly Cell-cell Junction Assembly Cell Junction Assembly Cell-cell Junction Organization	Synaptic Transmission Cell-cell Signaling Membrane Depolarization Regulation Of Membrane Potential Neurological System Process Cation Transmembrane Transport Ion Transmembrane Transport Neuron-neuron Synaptic Transmission Regulation Of Ion Transmembrane Transport Metal Ion Transport Ion Transport Cation Transport Signaling Cell Communication Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Transmembrane Transport Regulation Of Ion Transport Neuromuscular Process Regulation Of Neurological System Process Glutamate Receptor Signaling Pathway Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Potassium Ion Import Sensory Perception Of Pain Regulation Of Sensory Perception Of Pain Cell-cell Junction Organization Startle Response Monovalent Inorganic Cation Transport Directional Locomotion Membrane Depolarization During Action Potential Membrane Hyperpolarization Single-organism Behavior Gephyrin Clustering Transport Tight Junction Assembly Nervous System Development Regulation Of Resting Membrane Potential Postsynaptic Membrane Assembly Transmission Of Nerve Impulse Behavior Potassium Ion Transmembrane Transport Protein Localization To Membrane Glial Cell Differentiation Postsynaptic Density Protein 95 Clustering Neurogenesis Membrane Depolarization During Cardiac Muscle Cell Action Potential Apical Junction Assembly Potassium Ion Transport Response To Mechanical Stimulus
Tagcloud ?		acot11 adipose adiposity beige bfit brite brown chow cidea contributor cpt1beta dexa dio2 ehmt1 erralpha lean littermates orphan pparalpha resist roralpha sg stabilizes staggerer thermogenesis thermogenic thermography ucp1 uncoupling	10p12 255j24 adopter ak057360 ak078849 apicobasal av260217 bc038105 crb d10s588 drosoplila emp55 flj32798 gukc lin7a lin7b lin7c mpdz mpp2 mpp3 mpp7 mupp1 pals2 patj rp24 scrib scribble sdt stardust
Tagcloud (Difference) ?		acot11 adipose adiposity beige bfit brite brown chow cidea contributor cpt1beta dexa dio2 ehmt1 erralpha lean littermates orphan pparalpha resist roralpha sg stabilizes staggerer thermogenesis thermogenic thermography ucp1 uncoupling	10p12 255j24 adopter ak057360 ak078849 apicobasal av260217 bc038105 crb d10s588 drosoplila emp55 flj32798 gukc lin7a lin7b lin7c mpdz mpp2 mpp3 mpp7 mupp1 pals2 patj rp24 scrib scribble sdt stardust
Tagcloud (Intersection) ?