ABHD4 and AURKAIP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ABHD4	AURKAIP1
Description		abhydrolase domain containing 4, N-acyl phospholipase B	aurora kinase A interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Lipid Droplet	Nucleus Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Small Ribosomal Subunit Ribosome Ribonucleoprotein Complex
	Molecular Function	Phosphatidylcholine Lysophospholipase Activity Protein Binding Hydrolase Activity Lysophosphatidic Acid Acyltransferase Activity	Protein Binding
	Biological Process	Lipid Metabolic Process Glycerophospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Lipid Catabolic Process Phosphatidylethanolamine Acyl-chain Remodeling Lipid Homeostasis N-acylphosphatidylethanolamine Metabolic Process	Mitochondrial Translation Positive Regulation Of Proteolysis
Pathways		Acyl chain remodelling of PE	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Microalbuminuria ( 26631737)	Heel bone mineral density ( 30598549) Inflammatory bowel disease ( 28067908) Intraocular pressure ( 29617998) Ulcerative colitis ( 28067908)
Interacting Genes		14 interacting genes: AURKAIP1 BNIP2 CMTM5 COL4A5 CSNK2B DERL1 DGAT2L6 HTATIP2 IGFBP5 INSIG2 PLIN3 RABAC1 REEP5 TK1	6 interacting genes: ABHD4 AJUBA AURKA DEFB127 FAM9B GSK3A
Entrez ID		63874	54998
HPRD ID		12406	16457
Ensembl ID		ENSG00000100439	ENSG00000175756
Uniprot IDs		Q8TB40	Q9NWT8
PDB IDs			3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2
Enriched GO Terms of Interacting Partners?			Negative Regulation Of UDP-glucose Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Type B Pancreatic Cell Development Regulation Of Mitochondrion Organization Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Meiotic Cell Cycle Positive Regulation Of Proteolysis Autosome Genomic Imprinting Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Cellular Response To Interleukin-3 Regulation Of Glycogen (starch) Synthase Activity Spindle Assembly Involved In Female Meiosis I Pronucleus Germinal Vesicle Chromosome Passenger Complex Mitotic Centrosome Separation Histone H3S10 Kinase Activity Axon Hillock Positive Regulation Of Oocyte Maturation Glycerophospholipid Biosynthetic Process Phospholipid Biosynthetic Process Proximal Dendrite Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Cell Maturation N-acylphosphatidylethanolamine Metabolic Process Negative Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Glycerophospholipid Metabolic Process Regulation Of Microtubule-based Process Phosphatidylethanolamine Acyl-chain Remodeling Alpha-catenin Binding Cardiac Left Ventricle Morphogenesis Cilium Disassembly Lysophosphatidic Acid Acyltransferase Activity Beta-catenin Destruction Complex Centrosome Separation Spindle Assembly Involved In Female Meiosis
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