ABHD4 and HTATIP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ABHD4	HTATIP2
Description		abhydrolase domain containing 4, N-acyl phospholipase B	HIV-1 Tat interactive protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Lipid Droplet	Cytoplasm Mitochondrion Cytosol
	Molecular Function	Phosphatidylcholine Lysophospholipase Activity Protein Binding Hydrolase Activity Lysophosphatidic Acid Acyltransferase Activity	Catalytic Activity Protein Serine/threonine Kinase Activity Protein Binding
	Biological Process	Lipid Metabolic Process Glycerophospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Lipid Catabolic Process Phosphatidylethanolamine Acyl-chain Remodeling Lipid Homeostasis N-acylphosphatidylethanolamine Metabolic Process	Regulation Of Translation Positive Regulation Of Programmed Cell Death Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation
Pathways		Acyl chain remodelling of PE
Drugs			Polyethylene glycol 400
Diseases
GWAS		Metabolite levels ( 23823483) Microalbuminuria ( 26631737)	Bell's palsy ( 33602968) Fractional shortening ( 29403010) Obesity-related traits ( 23251661) Response to inhaled glucocorticoid treatment in asthma (change in FEV1) ( 25601762)
Interacting Genes		14 interacting genes: AURKAIP1 BNIP2 CMTM5 COL4A5 CSNK2B DERL1 DGAT2L6 HTATIP2 IGFBP5 INSIG2 PLIN3 RABAC1 REEP5 TK1	29 interacting genes: ABHD4 ACSL4 AQP6 ASF1A CD79A CFTR EHHADH ETS1 FAM209A FITM2 FKBP7 GET1 HDAC6 HSD17B11 JAGN1 JPH1 MIEF1 MTIF3 NCOA5 PITPNC1 PLIN2 RAB5A REEP4 RETREG3 SH3GLB1 SLC10A6 SLC18A1 TMEM115 TMX2
Entrez ID		63874	10553
HPRD ID		12406	09288
Ensembl ID		ENSG00000100439	ENSG00000109854
Uniprot IDs		Q8TB40	Q9BUP3
PDB IDs			2BKA
Enriched GO Terms of Interacting Partners?			Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Lipid Biosynthetic Process Lysophosphatidic Acid Acyltransferase Activity Endoplasmic Reticulum Organization Regulation Of Establishment Of Protein Localization Organelle Disassembly Fatty Acid Derivative Metabolic Process Alpha-linolenic Acid Metabolic Process
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