CXCL12 and CXCR4

  • Number of citations of the paper that reports this interaction (PMID 8752281)
  • 310
  • Data Source:
  • BioGRID (x-ray crystallography)
  • HPRD (in vivo, in vitro)

CXCL12

CXCR4

Gene Name chemokine (C-X-C motif) ligand 12 chemokine (C-X-C motif) receptor 4
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 10 interactors: CD4 CTSG CXCR4 DAZAP2 DPP4 ELANE FN1 MMP2 PF4 VCAN 32 interactors: ADRBK2 ARRB2 ATP13A2 CCR5 CD4 CTSG CXCL12 DPP4 ELANE GNA13 GNAI1 HLA-C HSPA8 ITCH JAK1 JAK2 JAK3 MYBL2 MYH9 PTK2 PTPN11 PTPN6 PTPRC SDC4 SOCS1 SOCS3 STAT1 STAT2 STAT3 STAT5B USP14 VAV1
Entrez ID 6387 7852
HPRD ID 02904 01217
Ensembl ID ENSG00000107562 ENSG00000121966
Uniprot IDs H7BYN8 P48061 P61073
PDB IDs 1A15 1QG7 1SDF 1VMC 2J7Z 2K01 2K03 2K04 2K05 2KEC 2KED 2KEE 2KOL 2NWG 2SDF 3GV3 3HP3 4LMQ 2K03 2K04 2K05 3ODU 3OE0 3OE6 3OE8 3OE9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adam23  adenomatous  apc  bc  bcs  cumulative  detecting  disintegrin  hypermethylation  informative  invasiveness  lnms  maintaining  manifested  metalloprotease  methylated  methylation  methylations  pl  polyposis  pts  pyrosequencing  quantification  quantify  rassf1a  software  spectrums  spss  utility 
capture  ccr1  ccr2  ccr5  ccr7  cd40  chemokine  chemokines  cxcr1  dc  dendritic  ebi1  elc  immature  inflamed  insight  lost  lymphoid  marginally  maturation  mature  maturing  migrate  nodes  organs  phases  respective  responded  responsiveness 
Tagcloud (Difference) ?
adam23  adenomatous  apc  bc  bcs  cumulative  detecting  disintegrin  hypermethylation  informative  invasiveness  lnms  maintaining  manifested  metalloprotease  methylated  methylation  methylations  pl  polyposis  pts  pyrosequencing  quantification  quantify  rassf1a  software  spectrums  spss  utility 
capture  ccr1  ccr2  ccr5  ccr7  cd40  chemokine  chemokines  cxcr1  dc  dendritic  ebi1  elc  immature  inflamed  insight  lost  lymphoid  marginally  maturation  mature  maturing  migrate  nodes  organs  phases  respective  responded  responsiveness 
Tagcloud (Intersection) ?