CCL20 and CXCL11

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		CCL20	CXCL11
Description		C-C motif chemokine ligand 20	C-X-C motif chemokine ligand 11
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CCR6 Chemokine Receptor Binding	Cytokine Activity Protein Binding Chemokine Activity Heparin Binding CXCR3 Chemokine Receptor Binding
	Biological Process	Chemotaxis Inflammatory Response Immune Response Signal Transduction Cell-cell Signaling Calcium-mediated Signaling Killing Of Cells Of Another Organism Defense Response To Bacterium Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide T Cell Migration Thymocyte Migration Positive Regulation Of T Cell Migration	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Killing Of Cells Of Another Organism Regulation Of Cell Population Proliferation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359) Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 30929738 31959851 32296059 34103634) Asthma (childhood onset) ( 30929738 31036433) Asthma onset (childhood vs adult) ( 30929738) Blood pressure ( 17903302) Crohn's disease ( 26192919) Eating disorders (purging via substances) ( 23568457) Inflammatory bowel disease ( 26192919) Primary biliary cholangitis ( 26394269) Ulcerative colitis ( 26192919)	Blood protein levels ( 30072576) Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
Interacting Genes		11 interacting genes: CCL5 CCR6 CXCL11 CXCL12 CXCL17 CXCL5 MTDH PF4 TGFB3 VCAN XCL2	25 interacting genes: CCL1 CCL11 CCL13 CCL20 CCL21 CCL24 CCL25 CCL26 CCL5 CCL8 CCR3 CXCL10 CXCL12 CXCL14 CXCL2 CXCL9 CXCR3 DPP4 LRRK2 MTUS2 PF4 PF4V1 PPBP SMARCB1 XCL1
Entrez ID		6364	6373
HPRD ID		03571	05329
Ensembl ID		ENSG00000115009	ENSG00000169248
Uniprot IDs		P78556	O14625
PDB IDs		1M8A 2HCI 2JYO 5UR7 6WWZ 7T1E	1RJT 8HNK
Enriched GO Terms of Interacting Partners?		Cell Chemotaxis Chemokine Activity Leukocyte Chemotaxis Chemotaxis Locomotion Cytokine Activity Mononuclear Cell Migration Leukocyte Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Humoral Immune Response Cell Migration Antimicrobial Humoral Response Cell Motility Chemokine-mediated Signaling Pathway Extracellular Space CXCR Chemokine Receptor Binding Cytokine-mediated Signaling Pathway Extracellular Region Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Monocyte Chemotaxis Myeloid Leukocyte Migration Regulation Of Monocyte Chemotaxis T Cell Migration Positive Regulation Of Chemotaxis Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Migration Immune Response Immune System Process Defense Response To Symbiont Defense Response To Other Organism G Protein-coupled Receptor Signaling Pathway Regulation Of T Cell Migration CXCR3 Chemokine Receptor Binding Cell Surface Receptor Signaling Pathway Defense Response Lymphocyte Migration Regulation Of Chemotaxis Regulation Of Leukocyte Migration Regulation Of Lymphocyte Migration Inflammatory Response Granulocyte Chemotaxis Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Chemokine Receptor Binding Positive Regulation Of Locomotion Granulocyte Migration Response To Other Organism Positive Regulation Of Calcium Ion Transport T Cell Chemotaxis	Chemokine Activity Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemotaxis Locomotion Antimicrobial Humoral Response Cytokine Activity Leukocyte Chemotaxis Humoral Immune Response Granulocyte Chemotaxis Chemokine-mediated Signaling Pathway Leukocyte Migration Granulocyte Migration Cell Migration Killing Of Cells Of Another Organism Myeloid Leukocyte Migration Cell Motility Inflammatory Response Cell Killing CCR Chemokine Receptor Binding Defense Response Eosinophil Chemotaxis Defense Response To Symbiont Eosinophil Migration Defense Response To Other Organism Immune Response Cytokine-mediated Signaling Pathway Immune System Process Response To Other Organism Extracellular Space Response To External Biotic Stimulus Regulation Of Leukocyte Migration G Protein-coupled Receptor Signaling Pathway Response To Stress CXCR Chemokine Receptor Binding Positive Regulation Of Locomotion Extracellular Region Mononuclear Cell Migration Regulation Of Locomotion Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Regulation Of Cell Migration Positive Regulation Of Leukocyte Migration Regulation Of Cell Motility Chemokine Receptor Binding Regulation Of Chemotaxis Positive Regulation Of T Cell Migration Positive Regulation Of Chemotaxis Positive Regulation Of Lymphocyte Migration Cell Surface Receptor Signaling Pathway
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