CCL20

Name	C-C motif chemokine ligand 20
Structure
Interactors	11 interactors: CCL5 CCR6 CXCL11 CXCL12 CXCL17 CXCL5 MTDH PF4 TGFB3 VCAN XCL2
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CCR6 Chemokine Receptor Binding
	Biological Process	Chemotaxis Inflammatory Response Immune Response Signal Transduction Cell-cell Signaling Calcium-mediated Signaling Killing Of Cells Of Another Organism Defense Response To Bacterium Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide T Cell Migration Thymocyte Migration Positive Regulation Of T Cell Migration
Pathways	Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling
GWAS	Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359 ) Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359 ) Allergic disease (asthma, hay fever or eczema) ( 29083406 ) Asthma ( 30929738 31959851 32296059 34103634 ) Asthma (childhood onset) ( 30929738 31036433 ) Asthma onset (childhood vs adult) ( 30929738 ) Blood pressure ( 17903302 ) Crohn's disease ( 26192919 ) Eating disorders (purging via substances) ( 23568457 ) Inflammatory bowel disease ( 26192919 ) Primary biliary cholangitis ( 26394269 ) Ulcerative colitis ( 26192919 )
Entrez ID	6364
HPRD ID	03571
Ensembl ID	ENSG00000115009
Uniprot IDs	P78556
PDB IDs	1M8A 2HCI 2JYO 5UR7 6WWZ 7T1E
GO Terms Enriched among Interactors ?	Cell Chemotaxis Chemokine Activity Leukocyte Chemotaxis Chemotaxis Locomotion Cytokine Activity Mononuclear Cell Migration Leukocyte Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Humoral Immune Response Cell Migration Antimicrobial Humoral Response Cell Motility Chemokine-mediated Signaling Pathway Extracellular Space CXCR Chemokine Receptor Binding Cytokine-mediated Signaling Pathway Extracellular Region Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Monocyte Chemotaxis Myeloid Leukocyte Migration Regulation Of Monocyte Chemotaxis T Cell Migration Positive Regulation Of Chemotaxis Regulation Of Mononuclear Cell Migration Positive Regulation Of Leukocyte Migration Immune Response Immune System Process Defense Response To Symbiont Defense Response To Other Organism G Protein-coupled Receptor Signaling Pathway Regulation Of T Cell Migration CXCR3 Chemokine Receptor Binding Cell Surface Receptor Signaling Pathway Defense Response Lymphocyte Migration Regulation Of Chemotaxis Regulation Of Leukocyte Migration Regulation Of Lymphocyte Migration Inflammatory Response Granulocyte Chemotaxis Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Chemokine Receptor Binding Positive Regulation Of Locomotion Granulocyte Migration Response To Other Organism Positive Regulation Of Calcium Ion Transport T Cell Chemotaxis