CCL1 and CXCL11

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down)

		CCL1	CXCL11
Description		C-C motif chemokine ligand 1	C-X-C motif chemokine ligand 11
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Chemokine Activity CCR Chemokine Receptor Binding	Cytokine Activity Protein Binding Chemokine Activity Heparin Binding CXCR3 Chemokine Receptor Binding
	Biological Process	Intracellular Calcium Ion Homeostasis Chemotaxis Inflammatory Response Immune Response Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Viral Process Positive Regulation Of Cell Migration Killing Of Cells Of Another Organism Positive Regulation Of Interleukin-17 Production Eosinophil Chemotaxis Positive Regulation Of Inflammatory Response Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Positive Regulation Of Monocyte Chemotaxis	Chemotaxis Defense Response Inflammatory Response Immune Response Signal Transduction Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling T Cell Chemotaxis Killing Of Cells Of Another Organism Regulation Of Cell Population Proliferation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Crohn's disease ( 22412388)	Blood protein levels ( 30072576) Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)
Interacting Genes		3 interacting genes: CCR8 CXCL11 HUWE1	25 interacting genes: CCL1 CCL11 CCL13 CCL20 CCL21 CCL24 CCL25 CCL26 CCL5 CCL8 CCR3 CXCL10 CXCL12 CXCL14 CXCL2 CXCL9 CXCR3 DPP4 LRRK2 MTUS2 PF4 PF4V1 PPBP SMARCB1 XCL1
Entrez ID		6346	6373
HPRD ID		01654	05329
Ensembl ID		ENSG00000108702	ENSG00000169248
Uniprot IDs		P22362	O14625
PDB IDs		1EL0 4OIJ 4OIK 8U1U	1RJT 8HNK
Enriched GO Terms of Interacting Partners?		Chemokine-mediated Signaling Pathway Locomotion Cell Chemotaxis Chemotaxis CXCR3 Chemokine Receptor Binding Histone Ubiquitin Ligase Activity Negative Regulation Of Mitochondrial Fusion Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Regulation Of Mitochondrial Fusion Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Type 2 Mitophagy T Cell Chemotaxis Ubiquitin-ubiquitin Ligase Activity Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Lymphocyte Chemotaxis Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Mitophagy Protein Branched Polyubiquitination Positive Regulation Of Autophagy Of Mitochondrion	Chemokine Activity Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemotaxis Locomotion Antimicrobial Humoral Response Cytokine Activity Leukocyte Chemotaxis Humoral Immune Response Granulocyte Chemotaxis Chemokine-mediated Signaling Pathway Leukocyte Migration Granulocyte Migration Cell Migration Killing Of Cells Of Another Organism Myeloid Leukocyte Migration Cell Motility Inflammatory Response Cell Killing CCR Chemokine Receptor Binding Defense Response Eosinophil Chemotaxis Defense Response To Symbiont Eosinophil Migration Defense Response To Other Organism Immune Response Cytokine-mediated Signaling Pathway Immune System Process Response To Other Organism Extracellular Space Response To External Biotic Stimulus Regulation Of Leukocyte Migration G Protein-coupled Receptor Signaling Pathway Response To Stress CXCR Chemokine Receptor Binding Positive Regulation Of Locomotion Extracellular Region Mononuclear Cell Migration Regulation Of Locomotion Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Regulation Of Cell Migration Positive Regulation Of Leukocyte Migration Regulation Of Cell Motility Chemokine Receptor Binding Regulation Of Chemotaxis Positive Regulation Of T Cell Migration Positive Regulation Of Chemotaxis Positive Regulation Of Lymphocyte Migration Cell Surface Receptor Signaling Pathway
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