CCL1

Description		C-C motif chemokine ligand 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Intracellular Calcium Ion Homeostasis Chemotaxis Inflammatory Response Immune Response Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Viral Process Positive Regulation Of Cell Migration Killing Of Cells Of Another Organism Positive Regulation Of Interleukin-17 Production Eosinophil Chemotaxis Positive Regulation Of Inflammatory Response Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Positive Regulation Of Monocyte Chemotaxis
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Crohn's disease ( 22412388)
Interacting Genes		3 interacting genes: CCR8 CXCL11 HUWE1
Entrez ID		6346
HPRD ID		01654
Ensembl ID		ENSG00000108702
Uniprot IDs		P22362
PDB IDs		1EL0 4OIJ 4OIK 8U1U
Enriched GO Terms of Interacting Partners?		Chemokine-mediated Signaling Pathway Locomotion Cell Chemotaxis Chemotaxis CXCR3 Chemokine Receptor Binding Histone Ubiquitin Ligase Activity Negative Regulation Of Mitochondrial Fusion Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Regulation Of Mitochondrial Fusion Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Type 2 Mitophagy T Cell Chemotaxis Ubiquitin-ubiquitin Ligase Activity Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Lymphocyte Chemotaxis Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Mitophagy Protein Branched Polyubiquitination Positive Regulation Of Autophagy Of Mitochondrion
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