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BGLAP and GGCX
Number of citations of the paper that reports this interaction (PMID
10393081
)
2
Data Source:
HPRD
(in vitro)
BGLAP
GGCX
Gene Name
bone gamma-carboxyglutamate (gla) protein
gamma-glutamyl carboxylase
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Cytoplasm
Rough Endoplasmic Reticulum
Golgi Apparatus
Dendrite
Membrane-bounded Vesicle
Perikaryon
Endoplasmic Reticulum Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Structural Molecule Activity
Calcium Ion Binding
Structural Constituent Of Bone
Hydroxyapatite Binding
Gamma-glutamyl Carboxylase Activity
Biological Process
Skeletal System Development
Osteoblast Differentiation
Osteoblast Development
Cell Adhesion
Cell Aging
Response To Mechanical Stimulus
Response To Gravity
Response To Zinc Ion
Response To Activity
Bone Mineralization
Regulation Of Bone Mineralization
Response To Vitamin K
Response To Vitamin D
Response To Testosterone
Response To Hydroxyisoflavone
Odontogenesis
Response To Drug
Response To Estrogen
Regulation Of Bone Resorption
Response To Ethanol
Regulation Of Osteoclast Differentiation
Response To Glucocorticoid
Bone Development
Cellular Response To Vitamin D
Cellular Response To Growth Factor Stimulus
Cellular Protein Modification Process
Blood Coagulation
Peptidyl-glutamic Acid Carboxylation
Post-translational Protein Modification
Cellular Protein Metabolic Process
Pathways
Post-translational protein modification
Gamma carboxylation, hypusine formation and arylsulfatase activation
Gamma-carboxylation of protein precursors
Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
Drugs
Menadione
Phytonadione
Gamma-Carboxy-Glutamic Acid
Gallium nitrate
Coagulation factor VIIa
Drotrecogin alfa
Coagulation Factor IX
L-Glutamic Acid
Menadione
Phytonadione
Anisindione
Diseases
GWAS
mean corpuscular hemoglobin concentration (
20139978
)
Prostate cancer (
21743467
)
Protein-Protein Interactions
5 interactors:
CTSB
CTSD
CTSH
CTSS
GGCX
6 interactors:
BGLAP
F10
F2
F7
F9
PROC
Entrez ID
632
2677
HPRD ID
00205
00665
Ensembl ID
ENSG00000115486
Uniprot IDs
P02818
P38435
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cellular Response To Thyroid Hormone Stimulus
Response To Thyroid Hormone
Collagen Catabolic Process
Collagen Metabolic Process
Multicellular Organismal Macromolecule Metabolic Process
Multicellular Organismal Metabolic Process
Extracellular Matrix Disassembly
Antigen Processing And Presentation
Extracellular Matrix Organization
Extracellular Structure Organization
Immune Response-regulating Signaling Pathway
Proteolysis
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II
Cellular Response To Hormone Stimulus
Catabolic Process
Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Immune System Process
Activation Of Innate Immune Response
Basement Membrane Disassembly
Neuropeptide Catabolic Process
Regulation Of Immune Response
Positive Regulation Of Innate Immune Response
Dichotomous Subdivision Of Terminal Units Involved In Lung Branching
Response To Hormone
Protein Metabolic Process
Antigen Processing And Presentation Of Peptide Antigen
Regulation Of Innate Immune Response
Bradykinin Catabolic Process
Adaptive Immune Response
Immune Response
Regulation Of Immune System Process
Peptidyl-glutamic Acid Carboxylation
T Cell Mediated Cytotoxicity
Surfactant Homeostasis
Peptide Catabolic Process
Chemical Homeostasis Within A Tissue
ERK1 And ERK2 Cascade
Decidualization
Basement Membrane Organization
Cellular Response To Organic Substance
Protein Destabilization
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Maternal Placenta Development
Leukocyte Mediated Cytotoxicity
Peptidyl-glutamic Acid Carboxylation
Blood Coagulation, Extrinsic Pathway
Post-translational Protein Modification
Blood Coagulation, Intrinsic Pathway
Blood Coagulation
Hemostasis
Protein Activation Cascade
Regulation Of Body Fluid Levels
Wound Healing
Response To Wounding
Response To Vitamin K
Peptidyl-amino Acid Modification
Regulation Of Blood Coagulation
Regulation Of Wound Healing
Proteolysis
Positive Regulation Of Blood Coagulation
Positive Regulation Of Coagulation
Positive Regulation Of Wound Healing
Negative Regulation Of Blood Coagulation
Negative Regulation Of Coagulation
Negative Regulation Of Wound Healing
Positive Regulation Of Protein Kinase B Signaling
Cellular Protein Modification Process
Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
Response To Vitamin
Response To Stress
Regulation Of Protein Kinase B Signaling
Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Positive Regulation Of Intracellular Signal Transduction
Cellular Protein Metabolic Process
Response To Estrogen
Response To Nutrient
Leukocyte Migration
Response To Stimulus
Response To Hydroxyisoflavone
Negative Regulation Of Fibrinolysis
Positive Regulation Of Signal Transduction
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Positive Regulation Of Cellular Component Movement
Positive Regulation Of Locomotion
Protein Metabolic Process
Regulation Of Fibrinolysis
Negative Regulation Of Astrocyte Differentiation
Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Response To Gravity
Negative Regulation Of Platelet Activation
Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Cellular Response To Vitamin D
Response To Nutrient Levels
Tagcloud
?
a2
a5
alkaline
altered
annexin
annexins
anxa2
anxa5
col1a1
else
fibrinolysis
generate
ibsp
knock
knockdown
mineralizing
osteoblasts
osteogenesis
osteogenic
osteoprogenitor
programming
psiren
rafts
responsiveness
runx2
shrna
si
stat6
vesicles
Tagcloud (Difference)
?
a2
a5
alkaline
altered
annexin
annexins
anxa2
anxa5
col1a1
else
fibrinolysis
generate
ibsp
knock
knockdown
mineralizing
osteoblasts
osteogenesis
osteogenic
osteoprogenitor
programming
psiren
rafts
responsiveness
runx2
shrna
si
stat6
vesicles
Tagcloud (Intersection)
?