GGCX

Gene Name		gamma-glutamyl carboxylase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Gamma-glutamyl Carboxylase Activity
	Biological Process	Cellular Protein Modification Process Blood Coagulation Peptidyl-glutamic Acid Carboxylation Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Post-translational protein modification Gamma carboxylation, hypusine formation and arylsulfatase activation Gamma-carboxylation of protein precursors Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
Drugs		Coagulation factor VIIa Drotrecogin alfa Coagulation Factor IX L-Glutamic Acid Menadione Phytonadione Anisindione
Diseases
GWAS		Prostate cancer ( 21743467)
Protein-protein Interactions		6 interactors: BGLAP F10 F2 F7 F9 PROC
Entrez ID		2677
HPRD ID		00665
Ensembl ID		ENSG00000115486
Uniprot IDs		P38435
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-glutamic Acid Carboxylation Blood Coagulation, Extrinsic Pathway Post-translational Protein Modification Blood Coagulation, Intrinsic Pathway Blood Coagulation Hemostasis Protein Activation Cascade Regulation Of Body Fluid Levels Wound Healing Response To Wounding Response To Vitamin K Peptidyl-amino Acid Modification Regulation Of Blood Coagulation Regulation Of Wound Healing Proteolysis Positive Regulation Of Blood Coagulation Positive Regulation Of Coagulation Positive Regulation Of Wound Healing Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Negative Regulation Of Wound Healing Positive Regulation Of Protein Kinase B Signaling Cellular Protein Modification Process Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Response To Vitamin Response To Stress Regulation Of Protein Kinase B Signaling Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Cellular Protein Metabolic Process Response To Estrogen Response To Nutrient Leukocyte Migration Response To Stimulus Response To Hydroxyisoflavone Negative Regulation Of Fibrinolysis Positive Regulation Of Signal Transduction Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Protein Metabolic Process Regulation Of Fibrinolysis Negative Regulation Of Astrocyte Differentiation Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Response To Gravity Negative Regulation Of Platelet Activation Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Cellular Response To Vitamin D Response To Nutrient Levels
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