BGLAP

Gene Name		bone gamma-carboxyglutamate (gla) protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Rough Endoplasmic Reticulum Golgi Apparatus Dendrite Membrane-bounded Vesicle Perikaryon
	Molecular Function	Structural Molecule Activity Calcium Ion Binding Structural Constituent Of Bone Hydroxyapatite Binding
	Biological Process	Skeletal System Development Osteoblast Differentiation Osteoblast Development Cell Adhesion Cell Aging Response To Mechanical Stimulus Response To Gravity Response To Zinc Ion Response To Activity Bone Mineralization Regulation Of Bone Mineralization Response To Vitamin K Response To Vitamin D Response To Testosterone Response To Hydroxyisoflavone Odontogenesis Response To Drug Response To Estrogen Regulation Of Bone Resorption Response To Ethanol Regulation Of Osteoclast Differentiation Response To Glucocorticoid Bone Development Cellular Response To Vitamin D Cellular Response To Growth Factor Stimulus
Pathways
Drugs		Menadione Phytonadione Gamma-Carboxy-Glutamic Acid Gallium nitrate
Diseases
GWAS		mean corpuscular hemoglobin concentration ( 20139978)
Protein-protein Interactions		5 interactors: CTSB CTSD CTSH CTSS GGCX
Entrez ID		632
HPRD ID		00205
Ensembl ID
Uniprot IDs		P02818
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Thyroid Hormone Stimulus Response To Thyroid Hormone Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Antigen Processing And Presentation Extracellular Matrix Organization Extracellular Structure Organization Immune Response-regulating Signaling Pathway Proteolysis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Cellular Response To Hormone Stimulus Catabolic Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Immune System Process Activation Of Innate Immune Response Basement Membrane Disassembly Neuropeptide Catabolic Process Regulation Of Immune Response Positive Regulation Of Innate Immune Response Dichotomous Subdivision Of Terminal Units Involved In Lung Branching Response To Hormone Protein Metabolic Process Antigen Processing And Presentation Of Peptide Antigen Regulation Of Innate Immune Response Bradykinin Catabolic Process Adaptive Immune Response Immune Response Regulation Of Immune System Process Peptidyl-glutamic Acid Carboxylation T Cell Mediated Cytotoxicity Surfactant Homeostasis Peptide Catabolic Process Chemical Homeostasis Within A Tissue ERK1 And ERK2 Cascade Decidualization Basement Membrane Organization Cellular Response To Organic Substance Protein Destabilization Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Maternal Placenta Development Leukocyte Mediated Cytotoxicity
Tagcloud ?		a2 a5 alkaline altered annexin annexins anxa2 anxa5 col1a1 else fibrinolysis generate ibsp knock knockdown mineralizing osteoblasts osteogenesis osteogenic osteoprogenitor programming psiren rafts responsiveness runx2 shrna si stat6 vesicles