RRBP1 and PRKD2

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
BioGRID (two hybrid)

		RRBP1	PRKD2
Gene Name		ribosome binding protein 1	protein kinase D2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Ribosome Membrane Integral Component Of Endoplasmic Reticulum Membrane	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Plasma Membrane
	Molecular Function	Receptor Activity Poly(A) RNA Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Kinase C Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Osteoblast Differentiation Translation Protein Transport	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Protein Phosphorylation Cell Adhesion Cell Death Positive Regulation Of Endothelial Cell Migration Peptidyl-serine Phosphorylation Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Interleukin-2 Production Positive Regulation Of Interleukin-8 Production Positive Regulation Of CREB Transcription Factor Activity Positive Regulation Of Peptidyl-serine Phosphorylation Intracellular Signal Transduction Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Angiogenesis Positive Regulation Of Cell Adhesion Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Autophosphorylation Vascular Endothelial Growth Factor Receptor Signaling Pathway T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Endothelial Tube Morphogenesis Positive Regulation Of ERK1 And ERK2 Cascade Protein Kinase D Signaling Positive Regulation Of Histone Deacetylase Activity Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of DNA Biosynthetic Process Positive Regulation Of Endothelial Cell Chemotaxis
Pathways
Drugs
Diseases
GWAS			Chronic lymphocytic leukemia ( 18758461)
Protein-Protein Interactions		4 interactors: ATF7IP KIF5B PRKD2 SMAD9	17 interactors: CASK DST GLRX3 GORASP1 GRIP1 HDAC7 HEY1 IFNAR1 MTF2 PDLIM7 PFDN1 PSG3 RARB RRBP1 RXRA SNRNP70 TGOLN2
Entrez ID		6238	25865
HPRD ID		11796	09523
Ensembl ID		ENSG00000125844	ENSG00000105287
Uniprot IDs		Q9P2E9	M0QZW1 M0R2R2 Q8NCK8 Q9BZL6
PDB IDs			2COA 3BGM
Enriched GO Terms of Interacting Partners?		Protein Kinase D Signaling Stress Granule Disassembly Positive Regulation Of Histone Deacetylase Activity Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Histone Deacetylase Activity Positive Regulation Of Deacetylase Activity Plus-end-directed Vesicle Transport Along Microtubule Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Cytoplasm Organization Mullerian Duct Regression Positive Regulation Of Endothelial Cell Chemotaxis Regulation Of Transcription From RNA Polymerase II Promoter Endothelial Tube Morphogenesis Regulation Of Cellular Component Organization Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Synaptic Transmission, GABAergic Positive Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of CREB Transcription Factor Activity Anatomical Structure Regression Positive Regulation Of DNA Biosynthetic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Cellular Response To Growth Factor Stimulus Positive Regulation Of Histone Deacetylation Response To Growth Factor Regulation Of DNA-templated Transcription, Initiation Anatomical Structure Morphogenesis Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Deacetylation Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Potassium Ion Transport Tube Development Positive Regulation Of Interleukin-8 Production Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Interleukin-2 Production Vesicle Transport Along Microtubule Regulation Of Synaptic Transmission, GABAergic Regulation Of Histone Deacetylation Organelle Disassembly Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization To Plasma Membrane Cellular Response To Vascular Endothelial Growth Factor Stimulus	Positive Regulation Of Gene Expression Regulation Of Osteoblast Differentiation Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Cardiac Chamber Development Developmental Process Positive Regulation Of Transcription, DNA-templated Retinoic Acid Receptor Signaling Pathway Ventricular Cardiac Muscle Cell Differentiation Cellular Response To Steroid Hormone Stimulus Multicellular Organismal Development Cardiac Muscle Tissue Development Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Ossification Intracellular Receptor Signaling Pathway Heart Development Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Heart Morphogenesis Ventricular Cardiac Muscle Tissue Morphogenesis Glandular Epithelial Cell Differentiation Cellular Response To Hormone Stimulus Negative Regulation Of Transcription, DNA-templated Ventricular Cardiac Muscle Tissue Development Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cardiac Muscle Tissue Morphogenesis Cardiac Septum Morphogenesis Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Ossification Regulation Of RNA Metabolic Process Muscle Tissue Morphogenesis Muscle Organ Morphogenesis Cardiac Ventricle Morphogenesis Positive Regulation Of Osteoblast Differentiation Striated Muscle Tissue Development Negative Regulation Of Cell Differentiation Muscle Cell Differentiation Negative Regulation Of Gene Expression Muscle Tissue Development Negative Regulation Of Biosynthetic Process Positive Regulation Of Translational Initiation By Iron Cardiac Septum Development Regulation Of Gene Expression Anatomical Structure Development Regulation Of Nitrogen Compound Metabolic Process Vasculogenesis Positive Regulation Of Ossification
Tagcloud ?		atf6 cardiomyopathies concordant contraction dcm dilated explanted failing folding grp78 hearts hf icm ire1 kinectin multifunctional nogo organelle perturbations plausible procollagen quantified relaxation reticulon shaping storage ventricular worse xbp1	a172 cdk2 crt0066101 dismal e2f1 gbm gbm2 gli25 glioblastoma glioma gliomagenesis gm133 hallmarks hypophosphorylation mer multiforme mut p15 pkb pkc prb profoundly retinoblastoma senescence silencing t98g u251 u87mg
Tagcloud (Difference) ?		atf6 cardiomyopathies concordant contraction dcm dilated explanted failing folding grp78 hearts hf icm ire1 kinectin multifunctional nogo organelle perturbations plausible procollagen quantified relaxation reticulon shaping storage ventricular worse xbp1	a172 cdk2 crt0066101 dismal e2f1 gbm gbm2 gli25 glioblastoma glioma gliomagenesis gm133 hallmarks hypophosphorylation mer multiforme mut p15 pkb pkc prb profoundly retinoblastoma senescence silencing t98g u251 u87mg
Tagcloud (Intersection) ?