RRAD and CAMK2G

Number of citations of the paper that reports this interaction (PMID 9115241)
26

Data Source:
BioGRID (pull down, enzymatic study, enzymatic study)
HPRD (in vitro)

		RRAD	CAMK2G
Gene Name		Ras-related associated with diabetes	calcium/calmodulin-dependent protein kinase II gamma
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane	Nucleoplasm Cytosol Plasma Membrane Membrane Endocytic Vesicle Membrane Sarcoplasmic Reticulum Membrane
	Molecular Function	GTPase Activity Protein Binding Calmodulin Binding GTP Binding	Calmodulin-dependent Protein Kinase Activity Calcium-dependent Protein Serine/threonine Phosphatase Activity Protein Binding Calmodulin Binding ATP Binding Protein Homodimerization Activity
	Biological Process	Small GTPase Mediated Signal Transduction	G1/S Transition Of Mitotic Cell Cycle Calcium Ion Transport Synaptic Transmission Nervous System Development Regulation Of Skeletal Muscle Adaptation Dephosphorylation Cytokine-mediated Signaling Pathway Insulin Secretion Cell Differentiation Cellular Response To Heat Protein Autophosphorylation Protein Oligomerization Regulation Of Calcium Ion Transport Interferon-gamma-mediated Signaling Pathway Regulation Of Cellular Response To Heat Regulation Of Relaxation Of Cardiac Muscle
Pathways			Interferon Signaling Cytokine Signaling in Immune system Cellular response to heat stress CREB phosphorylation through the activation of Ras Trafficking of AMPA receptors Interferon gamma signaling HSF1-dependent transactivation Activation of NMDA receptor upon glutamate binding and postsynaptic events CREB phosphorylation through the activation of CaMKII Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Unblocking of NMDA receptor, glutamate binding and activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ras activation uopn Ca2+ infux through NMDA receptor Post NMDA receptor activation events Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: CALM1 CAMK2G CSNK2A1 CSNK2B MMP14 NME1 PRKACA PRKCA PRKCB TPM2 YWHAZ	31 interactors: ACTN2 ACTN4 ADCY3 ATF1 CABP2 CALM1 CHAT CREM EGFR FLNA GRIA1 GRIA4 GRIN1 GRIN2B LRRC7 MYLK PEA15 PLCB3 PPM1F RCHY1 RRAD RYR1 SMAD2 SMAD3 SMAD4 SPR STAT1 STMN1 SYN1 TH TIAM1
Entrez ID		6236	818
HPRD ID		01536	03672
Ensembl ID		ENSG00000166592	ENSG00000148660
Uniprot IDs		P55042	Q13280 Q13555 Q5SWX3
PDB IDs		2DPX 2GJS 3Q72 3Q7P 3Q7Q	2UX0 2V7O
Enriched GO Terms of Interacting Partners?		Histone H3-T6 Phosphorylation Phosphorylation Platelet Activation Negative Regulation Of Glucose Transport Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Dense Core Granule Biogenesis Regulation Of Rhodopsin Mediated Signaling Pathway Activation Of Adenylate Cyclase Activity Phosphate-containing Compound Metabolic Process Rhodopsin Mediated Signaling Pathway Mitotic Cell Cycle Positive Regulation Of Adenylate Cyclase Activity Mitotic Nuclear Envelope Disassembly Negative Regulation Of Insulin Receptor Signaling Pathway Blood Coagulation Hemostasis Nuclear Envelope Disassembly Histone Phosphorylation Regulation Of Blood Vessel Endothelial Cell Migration Peptidyl-threonine Phosphorylation Positive Regulation Of Lyase Activity Cell-cell Signaling Activation Of Phospholipase C Activity Regulation Of Adenylate Cyclase Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of CAMP Biosynthetic Process Regulation Of Insulin Receptor Signaling Pathway Regulation Of Cyclase Activity Regulation Of Body Fluid Levels Nuclear Envelope Organization Positive Regulation Of CAMP Metabolic Process Synaptic Transmission Wound Healing Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Phospholipase Activity Cellular Response To Carbohydrate Stimulus Phototransduction, Visible Light Regulation Of Cellular Response To Insulin Stimulus Positive Regulation Of Cyclic Nucleotide Metabolic Process Positive Regulation Of Protein Metabolic Process Cell Activation Regulation Of Phospholipase Activity Mitotic Cell Cycle Process Regulation Of CAMP Biosynthetic Process Positive Regulation Of Lipase Activity Positive Regulation Of Signal Transduction Detection Of Visible Light Response To Wounding Desmosome Assembly	Signaling Cell Communication Synaptic Transmission Cellular Response To Stimulus Cell-cell Signaling Response To Organic Cyclic Compound Enzyme Linked Receptor Protein Signaling Pathway Response To Stimulus Cellular Response To Growth Factor Stimulus Neuron-neuron Synaptic Transmission Signal Transduction Response To Growth Factor Response To Abiotic Stimulus Response To Organic Substance SMAD Protein Complex Assembly Cell Development Intracellular Signal Transduction Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Cellular Process Response To Organonitrogen Compound Cell Differentiation Cell Projection Organization Regulation Of Signaling Glutamate Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway System Development Multicellular Organismal Development Neuron Development Regulation Of Synaptic Transmission Platelet Degranulation Cell Morphogenesis Involved In Differentiation Positive Regulation Of Transport Secretion By Cell Anatomical Structure Morphogenesis Positive Regulation Of Cellular Component Movement Response To Stress Mesenchyme Development Organ Development Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Protein Import Into Nucleus Neuron Differentiation Cell Morphogenesis Involved In Neuron Differentiation Neurotrophin TRK Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Neurotrophin Signaling Pathway Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport Response To Amphetamine
Tagcloud ?		abolishes antagonizing biosynthetic blocking contributes demands display drives ectopic energetic glut1 glycolysis greatly hypoxia hypoxic meet microenvironmental newly normoxia p53 promotes reduces represses repressing stimulating suppression switch translocation turn	agouti cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Difference) ?		abolishes antagonizing biosynthetic blocking contributes demands display drives ectopic energetic glut1 glycolysis greatly hypoxia hypoxic meet microenvironmental newly normoxia p53 promotes reduces represses repressing stimulating suppression switch translocation turn	agouti cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Intersection) ?