RPS15A and ELF5

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		RPS15A	ELF5
Description		ribosomal protein S15a	E74 like ETS transcription factor 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Ribosome Membrane Cytosolic Ribosome Cytosolic Small Ribosomal Subunit Small-subunit Processome Extracellular Exosome Ribonucleoprotein Complex	Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cytoplasmic Translation Translation Positive Regulation Of Cell Population Proliferation Response To Virus Ribosomal Small Subunit Biogenesis Positive Regulation Of Cell Cycle	Ectodermal Cell Fate Commitment Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Ectoderm Development Cell Differentiation Somatic Stem Cell Population Maintenance Positive Regulation Of Transcription By RNA Polymerase II Mammary Gland Epithelial Cell Differentiation Trophoblast Giant Cell Differentiation Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency SARS-CoV-1 modulates host translation machinery SARS-CoV-2 modulates host translation machinery Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	Developmental Lineage of Mammary Gland Luminal Epithelial Cells Developmental Lineage of Mammary Gland Alveolar Cells
Drugs
Diseases
GWAS		Caffeine consumption from coffee or tea ( 33287642) Refractive error ( 32231278)	β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Metabolite levels ( 23823483)
Interacting Genes		13 interacting genes: CALM1 CDC37 DDX39B DUX4 ELF5 ERCC6 EWSR1 FBXO7 FOXP1 PTEN RHOU UBE3A VHL	11 interacting genes: ACTR2 CRBN FRZB GLRX2 NFE2 NFE2L2 NRIP2 RPS15A SIRT6 SS18L1 UBQLN4
Entrez ID		6210	2001
HPRD ID		04723	05525
Ensembl ID		ENSG00000134419	ENSG00000135374
Uniprot IDs		P62244	A0A087X1W9 A8K443 Q9UKW6
PDB IDs		4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZUO 6ZV6 6ZVH 6ZVJ 6ZXD 6ZXE 6ZXF 6ZXG 6ZXH 7A09 7K5I 7MQ8 7MQ9 7MQA 7QP6 7QP7 7R4X 7TQL 7WTS 7WTT 7WTU 7WTV 7WTW 7WTX 7WTZ 7WU0 7XNX 7XNY 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IFD 8IFE 8JDJ 8JDK 8JDL 8JDM 8K2C 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPK 8PPL 8QOI 8T4S 8UKB 8XP2 8XP3 8XSX 8XSY 8XSZ 8XXL 8XXM 8XXN 8Y0W 8Y0X 8YOO 8YOP 8ZDB 8ZDC 8ZDD 9BKD 9BLN 9C3H 9G8M 9G8O	1WWX
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Cycle Process Positive Regulation Of Metabolic Process Negative Regulation Of Cell Cycle Process Negative Regulation Of Cell Cycle Regulation Of Protein Stability Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Mitophagy Positive Regulation Of Autophagy Of Mitochondrion Protein Kinase Binding Nucleoplasm Regulation Of Signal Transduction Nucleus Regulation Of Intracellular Signal Transduction Regulation Of Cell Cycle Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Cell Cycle Phase Transition Negative Regulation Of Synaptic Vesicle Clustering Protein Stabilization Negative Regulation Of Organ Growth Sperm Entry Positive Regulation Of Golgi Lumen Acidification Regulation Of Autophagy Of Mitochondrion Regulation Of Mitophagy Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Ubiquitin-protein Transferase Activity Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Cell Communication Negative Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Biological Quality Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Signaling Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cell Differentiation Regulation Of RNA Metabolic Process Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Ectodermal Cell Fate Commitment Regulation Of Transcription By RNA Polymerase II Regulation Of Protein Modification Process Protein Modification By Small Protein Conjugation Positive Regulation Of Peptidyl-serine Phosphorylation Of STAT Protein Protein Ubiquitination Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Cellular Component Organization Regulation Of Nucleobase-containing Compound Metabolic Process Protein-DNA Complex Integrated Stress Response Signaling Nucleus Positive Regulation Of Cellular Component Organization Cell Redox Homeostasis Regulation Of Cellular Response To Stress Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Regulation Of DNA Repair Site Of DNA Damage Negative Regulation Of Hepatocyte Differentiation Positive Regulation Of Glutathione Biosynthetic Process Regulation Of D-glucose Import Arsenate Reductase (glutaredoxin) Activity Histone H3K56 Deacetylase Activity, NAD-dependent Positive Regulation Of Fat Cell Differentiation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Stem Cell Differentiation Regulation Of Glutathione Biosynthetic Process Regulation Of D-glucose Transmembrane Transport Aflatoxin Catabolic Process Glutathione Disulfide Oxidoreductase Activity Histone H3K9 Deacetylase Activity, Hydrolytic Mechanism Chromosome, Subtelomeric Region Histone H3K9 Deacetylase Activity, NAD-dependent NAD-dependent Protein Depalmitoylase Activity Histone H3K18 Deacetylase Activity, NAD-dependent NAD-dependent Protein Demyristoylase Activity Nuclear Proteasome Complex Positive Regulation Of Cell Projection Organization Regulation Of Protein Catabolic Process Regulation Of Proteolysis Positive Regulation Of Double-strand Break Repair Site Of Double-strand Break Cellular Response To Stress Regulation Of RNA Metabolic Process Meiotic Chromosome Movement Towards Spindle Pole Positive Regulation Of Protein Localization To Chromatin Negative Regulation Of Autophagosome Maturation Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Proteasomal Ubiquitin-independent Protein Catabolic Process
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