RPL8 and DPH3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RPL8	DPH3
Gene Name		ribosomal protein L8	diphthamide biosynthesis 3
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Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Binding Structural Constituent Of Ribosome RRNA Binding Poly(A) RNA Binding	Protein Binding Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Post-translational Protein Modification Cellular Protein Metabolic Process Negative Regulation Of Protein Secretion Positive Regulation Of Binding
Pathways		Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Synthesis of diphthamide-EEF2 Post-translational protein modification Gamma carboxylation, hypusine formation and arylsulfatase activation
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ARIH2 ARL15 C11orf49 CHDH DPH3 DUSP23 FAM188A FGFR3 IL7R NUDT3 ST3GAL3 UPF2	4 interactors: ADIPOR1 PIH1D2 RPL8 SERGEF
Entrez ID		6132	285381
HPRD ID		16044	16412
Ensembl ID		ENSG00000161016
Uniprot IDs		P62917	Q96FX2
PDB IDs		3J3B	2JR7
Enriched GO Terms of Interacting Partners?		Diphosphoinositol Polyphosphate Catabolic Process Diadenosine Polyphosphate Catabolic Process Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Interleukin-7-mediated Signaling Pathway Glycine Betaine Biosynthetic Process From Choline Growth	Leptin-mediated Signaling Pathway Adiponectin-activated Signaling Pathway Positive Regulation Of Ran GTPase Activity Cellular Response To Leptin Stimulus Response To Leptin
Tagcloud ?		3a aldolase apex1 athanogene beclin1 bim bisphosphate calpain endosialin erb erythroblastic ezrin fms fructose hes1 hmgb1 hydroxysteroid metalloproteinases midkine minibrain mmps osteosarcoma polo proto recql4 shed sulfotransferase vegfa wwox
Tagcloud (Difference) ?		3a aldolase apex1 athanogene beclin1 bim bisphosphate calpain endosialin erb erythroblastic ezrin fms fructose hes1 hmgb1 hydroxysteroid metalloproteinases midkine minibrain mmps osteosarcoma polo proto recql4 shed sulfotransferase vegfa wwox
Tagcloud (Intersection) ?