RP2 and PM20D2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RP2	PM20D2
Description		RP2 activator of ARL3 GTPase	peptidase M20 domain containing 2
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Centriole Cytosol Plasma Membrane Cilium Membrane Nuclear Body Cytoplasmic Vesicle Ciliary Basal Body Cell Projection Extracellular Exosome Periciliary Membrane Compartment	Nucleoplasm Cytoplasm
	Molecular Function	Nucleotide Binding Magnesium Ion Binding GTPase Activator Activity Protein Binding GTP Binding Unfolded Protein Binding	Carboxypeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity Dipeptidase Activity Identical Protein Binding Para-aminobenzoyl-glutamate Hydrolase Activity
	Biological Process	Protein Folding Post-Golgi Vesicle-mediated Transport Post-chaperonin Tubulin Folding Pathway Visual Perception Protein Transport Cilium Assembly	Proteolysis Folic Acid Catabolic Process Regulation Of Protein Metabolic Process
Pathways		Trafficking of myristoylated proteins to the cilium
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS			Serum metabolite levels ( 33031748)
Interacting Genes		2 interacting genes: ARL3 PM20D2	24 interacting genes: CERT1 CNNM3 DALRD3 DDIT4L DNAJC11 EPDR1 HAPLN2 KEL KRT75 KRTAP26-1 MEOX1 MYOZ3 NAA80 OGT POU6F2 PSMA1 REL RGS12 RP2 RUSC1 SAXO1 SIVA1 TAPBPL TDO2
Entrez ID		6102	135293
HPRD ID		02424	16473
Ensembl ID		ENSG00000102218	ENSG00000146281
Uniprot IDs		A0A1B2JLU2 O75695	Q8IYS1
PDB IDs		2BX6 3BH6 3BH7	7YH4 8XZC
Enriched GO Terms of Interacting Partners?		Folic Acid Catabolic Process Para-aminobenzoyl-glutamate Hydrolase Activity Protein Localization To Ciliary Membrane Folic Acid Metabolic Process Dipeptidase Activity Dicarboxylic Acid Catabolic Process Pteridine-containing Compound Metabolic Process Vitamin Metabolic Process Modified Amino Acid Catabolic Process Folic Acid-containing Compound Metabolic Process Carboxypeptidase Activity Photoreceptor Cell Development Spindle Microtubule Photoreceptor Connecting Cilium Intraciliary Transport Cytoplasmic Microtubule Protein Localization To Cilium Golgi To Plasma Membrane Transport Mitotic Cytokinesis GDP Binding
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