RP2 and ARL3

Number of citations of the paper that reports this interaction (PMID 11847227)
22

Data Source:
BioGRID (pull down)
HPRD (in vitro, in vivo)

		RP2	ARL3
Gene Name		retinitis pigmentosa 2 (X-linked recessive)	ADP-ribosylation factor-like 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Centriole Plasma Membrane Cytoplasmic Vesicle Ciliary Basal Body Extracellular Vesicular Exosome Primary Cilium Periciliary Membrane Compartment	Golgi Membrane Nucleus Golgi Apparatus Centrosome Spindle Microtubule Cytoplasmic Microtubule Midbody Photoreceptor Connecting Cilium Extracellular Vesicular Exosome Primary Cilium
	Molecular Function	Actin Binding Nucleoside Diphosphate Kinase Activity GTPase Activator Activity Protein Binding ATP Binding GTP Binding Unfolded Protein Binding	GTPase Activity Protein Binding GTP Binding Microtubule Binding GDP Binding Metal Ion Binding
	Biological Process	Cell Morphogenesis Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process Protein Folding Post-Golgi Vesicle-mediated Transport Organelle Organization Cytoskeleton Organization Post-chaperonin Tubulin Folding Pathway Visual Perception Protein Transport Positive Regulation Of GTPase Activity	Cytokinesis Kidney Development Post-Golgi Vesicle-mediated Transport Organelle Organization Smoothened Signaling Pathway Small GTPase Mediated Signal Transduction Protein Transport Intraciliary Transport Photoreceptor Cell Development Cilium Morphogenesis
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Trafficking of myristoylated proteins to the cilium Assembly of the primary cilium	Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Trafficking of myristoylated proteins to the cilium Assembly of the primary cilium
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		1 interactors: ARL3	10 interactors: ARL2BP GOLGA4 LRIF1 PDE6D RP2 TLE1 TP53 TUBA1A UBR1 UNC119
Entrez ID		6102	403
HPRD ID		02424	05260
Ensembl ID		ENSG00000102218	ENSG00000138175
Uniprot IDs		O75695	P36405
PDB IDs		2BX6 3BH6 3BH7
Enriched GO Terms of Interacting Partners?		Intraciliary Transport Photoreceptor Cell Development Post-Golgi Vesicle-mediated Transport Cytokinesis Smoothened Signaling Pathway Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport	Positive Regulation Of Peptidyl-tyrosine Phosphorylation Visual Perception Sensory Perception Of Light Stimulus Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Clathrin-mediated Endocytosis Regulation Of Cellular Amino Acid Metabolic Process Protein Localization Post-Golgi Vesicle-mediated Transport Negative Regulation Of Macromitophagy Cellular Response To Leucine Negative Regulation Of Caveolin-mediated Endocytosis Oligodendrocyte Apoptotic Process Regulation Of Cellular Ketone Metabolic Process Protein Localization To Organelle Cytokinesis, Completion Of Separation Negative Regulation Of Helicase Activity Notch Signaling Pathway Regulation Of Catalytic Activity Cellular Localization Protein Transport Protein Localization To Nucleus Establishment Of Protein Localization Mitotic Cell Cycle Process Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging Intracellular Transport Mitochondrial DNA Repair Response To Leucine Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Protein Phosphorylation Mitotic Cell Cycle Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Mitotic Cytokinetic Process Glial Cell Apoptotic Process Oxidative Stress-induced Premature Senescence Sensory Perception Regulation Of Intracellular Signal Transduction ER Overload Response Positive Regulation Of Phosphorylation Negative Regulation Of Macroautophagy Stress-induced Premature Senescence
Tagcloud ?		challenges combinations consequences deal dichotomized diphosphate displaying face great hetero hexamers highlight motility ndpk ndpks nm23 nme nme1 nmes nucleoside oligomers perhaps redundancy span spread surprising taxonomically typically uncertainty	accord brucei congolense conservation cruzi donovani eukaryotes flanking genesis leishmania monophyly multigene organization parasites phylogeny primitive protozoan rab1 reconstitution representatives s12 salivarian transporter trypanosoma trypanosomatids trypanosomes unicellular vivax ypt6
Tagcloud (Difference) ?		challenges combinations consequences deal dichotomized diphosphate displaying face great hetero hexamers highlight motility ndpk ndpks nm23 nme nme1 nmes nucleoside oligomers perhaps redundancy span spread surprising taxonomically typically uncertainty	accord brucei congolense conservation cruzi donovani eukaryotes flanking genesis leishmania monophyly multigene organization parasites phylogeny primitive protozoan rab1 reconstitution representatives s12 salivarian transporter trypanosoma trypanosomatids trypanosomes unicellular vivax ypt6
Tagcloud (Intersection) ?