ATG101 and ATG4A

Number of citations of the paper that reports this interaction (PubMedID 24100292)
45

Data Source:
BioGRID (two hybrid)

		ATG101	ATG4A
Description		autophagy related 101	autophagy related 4A cysteine peptidase
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GO Annotations	Cellular Component	Phagophore Assembly Site Cytoplasm Endoplasmic Reticulum Membrane Cytosol Atg1/ULK1 Kinase Complex	Cytoplasm
	Molecular Function	Protein Binding Protein Kinase Binding Identical Protein Binding Protein-containing Complex Binding	Cysteine-type Endopeptidase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Protein-phosphatidylethanolamide Deconjugating Activity
	Biological Process	Autophagosome Assembly Autophagy Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy	Autophagosome Assembly Mitophagy Proteolysis Lipid Metabolic Process Autophagy Protein Transport Protein Processing Piecemeal Microautophagy Of The Nucleus Aggrephagy Protein Delipidation
Pathways		Macroautophagy	Macroautophagy
Drugs
Diseases
GWAS
Interacting Genes		6 interacting genes: ATG13 ATG4A CSNK2B GABARAP MYL3 PTCH1	5 interacting genes: ATG101 CDKL3 GABARAPL1 GABARAPL2 MAP1LC3B
Entrez ID		60673	115201
HPRD ID		08566	06455
Ensembl ID		ENSG00000123395	ENSG00000101844
Uniprot IDs		Q9BSB4	B4DEA4 Q8WYN0
PDB IDs		4WZG 5C50 5XUY 5XV1 5XV3 5XV4 5XV6 8DO8	2P82
Enriched GO Terms of Interacting Partners?		Mitophagy Autophagy Of Mitochondrion Autophagosome Organization Autophagosome Assembly Protein Kinase Regulator Activity Macroautophagy Piecemeal Microautophagy Of The Nucleus Vacuole Organization Microautophagy Nucleophagy Autophagy Tissue Morphogenesis Neural Plate Axis Specification Autophagosome Epithelial Tube Morphogenesis Myosin II Heavy Chain Binding Response To Chlorate Negative Regulation Of Cell Population Proliferation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Muscle Tissue Development Intracellular Protein Localization Epidermal Cell Fate Specification Smoothened Binding Hedgehog Family Protein Binding Hedgehog Receptor Activity Organelle Assembly Positive Regulation Of Protein K48-linked Ubiquitination Protein-phosphatidylethanolamide Deconjugating Activity Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Processing Release From Viral Latency Protein Delipidation Positive Regulation Of Activin Receptor Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Viral Life Cycle Response To Mitochondrial Depolarisation Regulation Of Protein K48-linked Ubiquitination Adiponectin-activated Signaling Pathway Patched Binding Cell Proliferation Involved In Metanephros Development Mammary Gland Duct Morphogenesis Neural Tube Patterning Dendritic Growth Cone Regulation Of Protein Localization Atg1/ULK1 Kinase Complex Neural Tube Formation Metanephric Collecting Duct Development Cell Proliferation Involved In Kidney Development	Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Autophagosome Assembly Autophagosome Organization Vacuole Organization Autophagosome Maturation Autophagosome Membrane Mitophagy Autophagy Autophagy Of Mitochondrion Autophagosome Phospholipid Binding Protein-containing Complex Disassembly Macroautophagy GABA Receptor Binding Cellular Response To Starvation Organelle Assembly Response To Starvation Cellular Response To Nutrient Levels Ubiquitin Protein Ligase Binding Beta-tubulin Binding Response To Nutrient Levels Catabolic Process Cytoplasmic Vesicle Cellular Component Assembly Organelle Organization Microtubule Binding Atg1/ULK1 Kinase Complex Ceramide Binding Tat Protein Binding Dendrite Extension Glycophagy Microtubule Protein Localization To Endoplasmic Reticulum Protein-containing Complex Organization Positive Regulation Of ATP-dependent Activity Glycogen Catabolic Process Cellular Response To Stress Polysaccharide Catabolic Process Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Axon Extension Phagophore Assembly Site Intra-Golgi Vesicle-mediated Transport Regulation Of ATP-dependent Activity Positive Regulation Of Dendrite Morphogenesis Cytoplasm Organelle Membrane
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