RNASEL and ABCE1

Number of citations of the paper that reports this interaction (PMID 7539425)
42

Data Source:
HPRD (in vitro)

		RNASEL	ABCE1
Gene Name		ribonuclease L (2,5-oligoisoadenylate synthetase-dependent)	ATP-binding cassette, sub-family E (OABP), member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Mitochondrion Cytosol Nuclear Matrix	Cytoplasm Mitochondrion Membrane
	Molecular Function	RNA Binding Endoribonuclease Activity Protein Kinase Activity Protein Binding ATP Binding RRNA Binding Metal Ion Binding	ATP Binding Ribonuclease Inhibitor Activity ATPase Activity Iron-sulfur Cluster Binding
	Biological Process	RRNA Processing MRNA Processing Protein Phosphorylation Cytokine-mediated Signaling Pathway Negative Regulation Of Viral Genome Replication Positive Regulation Of Transcription From RNA Polymerase II Promoter Defense Response To Virus Type I Interferon Signaling Pathway RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	RNA Catabolic Process Response To Virus Viral Process Negative Regulation Of Catalytic Activity
Pathways		Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Multiple sclerosis ( 23412934)
Protein-Protein Interactions		3 interactors: ABCE1 AR TCF12	2 interactors: RNASE2 RNASEL
Entrez ID		6041	6059
HPRD ID		01590	03132
Ensembl ID		ENSG00000135828	ENSG00000164163
Uniprot IDs		Q05823 Q6AI46	P61221
PDB IDs		1WDY 4G8K 4G8L
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Integrin Biosynthetic Process Positive Regulation Of Integrin Biosynthetic Process Regulation Of Integrin Biosynthetic Process	RNA Phosphodiester Bond Hydrolysis, Endonucleolytic RNA Phosphodiester Bond Hydrolysis Nucleic Acid Phosphodiester Bond Hydrolysis
Tagcloud ?		abnormality balancing blocking candidates controlling eif2 hematopoietic icsbp interferon involve irf isgs kappa kind knock leads looks mediates myelogenous oas oncogene phosphorylate pkr possibilities probably proliferative roles transduction undergoes	aberrant codons decay dom34 drosophila e3 eliminate encounter erf1 eukaryotic homolog ligase ltn1 machineries mrnas nonstop nsd polypeptide proteasome recycling rescue ribosome ribosomes rqc stop translational triggered triggering uncovered
Tagcloud (Difference) ?		abnormality balancing blocking candidates controlling eif2 hematopoietic icsbp interferon involve irf isgs kappa kind knock leads looks mediates myelogenous oas oncogene phosphorylate pkr possibilities probably proliferative roles transduction undergoes	aberrant codons decay dom34 drosophila e3 eliminate encounter erf1 eukaryotic homolog ligase ltn1 machineries mrnas nonstop nsd polypeptide proteasome recycling rescue ribosome ribosomes rqc stop translational triggered triggering uncovered
Tagcloud (Intersection) ?