RNASEL

Gene Name		ribonuclease L (2,5-oligoisoadenylate synthetase-dependent)
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Gene Ontology Annotations	Cellular Component	Cellular_component Mitochondrion Cytosol Nuclear Matrix
	Molecular Function	RNA Binding Endoribonuclease Activity Protein Kinase Activity Protein Binding ATP Binding RRNA Binding Metal Ion Binding
	Biological Process	RRNA Processing MRNA Processing Protein Phosphorylation Cytokine-mediated Signaling Pathway Negative Regulation Of Viral Genome Replication Positive Regulation Of Transcription From RNA Polymerase II Promoter Defense Response To Virus Type I Interferon Signaling Pathway RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Multiple sclerosis ( 23412934)
Protein-protein Interactions		3 interactors: ABCE1 AR TCF12
Entrez ID		6041
HPRD ID		01590
Ensembl ID		ENSG00000135828
Uniprot IDs		Q05823 Q6AI46
PDB IDs		1WDY 4G8K 4G8L
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Integrin Biosynthetic Process Positive Regulation Of Integrin Biosynthetic Process Regulation Of Integrin Biosynthetic Process
Tagcloud ?		abnormality balancing blocking candidates controlling eif2 hematopoietic icsbp interferon involve irf isgs kappa kind knock leads looks mediates myelogenous oas oncogene phosphorylate pkr possibilities probably proliferative roles transduction undergoes