RFX2 and RFX1

Number of citations of the paper that reports this interaction (PMID 10330134)
16

Data Source:
HPRD (in vitro)

		RFX2	RFX1
Gene Name		regulatory factor X, 2 (influences HLA class II expression)	regulatory factor X, 1 (influences HLA class II expression)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Immune Response
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: MDFI RFX1 RFX4 RFX6	14 interactors: ABL1 ADD1 HIVEP2 HMGB1 MAGED1 NFIB NFIC NFIX RFX2 RFX3 SMAD1 SMAD4 SMAD9 TADA3
Entrez ID		5990	5989
HPRD ID		00824	02476
Ensembl ID		ENSG00000087903	ENSG00000132005
Uniprot IDs		P48378	P22670
PDB IDs			1DP7
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Dorsal/ventral Pattern Formation Pancreatic D Cell Differentiation Pancreatic Epsilon Cell Differentiation Transcription From RNA Polymerase II Promoter Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Pancreatic A Cell Differentiation Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Pattern Specification Process Trophoblast Giant Cell Differentiation Transcription, DNA-templated Cytoplasmic Sequestering Of Transcription Factor Dorsal/ventral Axis Specification Dorsal Spinal Cord Development RNA Biosynthetic Process Type B Pancreatic Cell Differentiation Regulation Of Protein Transport Enteroendocrine Cell Differentiation Cytoplasmic Sequestering Of Protein Regulation Of Establishment Of Protein Localization Positive Regulation Of Cellular Metabolic Process Spinal Cord Dorsal/ventral Patterning Cell Differentiation Involved In Embryonic Placenta Development Negative Regulation Of Smoothened Signaling Pathway Spinal Cord Patterning Activation Of JUN Kinase Activity Regulation Of Protein Localization Cerebellar Cortex Morphogenesis Negative Regulation Of DNA Binding Organ Development Glandular Epithelial Cell Differentiation Regulation Of Signaling Negative Regulation Of Transcription Factor Import Into Nucleus Cerebellum Morphogenesis Hindbrain Morphogenesis RNA Metabolic Process Endocrine Pancreas Development Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Cellular Localization Cerebellar Cortex Development Gene Expression Positive Regulation Of JUN Kinase Activity Negative Regulation Of Signal Transduction	Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Hindbrain Development Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Anatomical Structure Morphogenesis Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Organ Development BMP Signaling Pathway Regulation Of Binding System Development SMAD Protein Complex Assembly Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Multicellular Organismal Development Mesonephros Development Biosynthetic Process Brain Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Development Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud ?		asymmetry cilia ciliogenesis details foxj1a gpcr gpcrs gpr22 knock kupffer kv lefty1 lefty2 looping lpm lr master mesodermal morpholino organelles orphan patterning pitx2a player protrude randomization southpaw tem vesicle	243r abrogated adenovirus antagonizes cooperative disrupt e1a eh1 electrophoretic exerted implying kannabiran labrie mathews morris mutational nucleic oncoprotein p107 pcna proliferating relieves repress res retain suggestive transactivating unable virol
Tagcloud (Difference) ?		asymmetry cilia ciliogenesis details foxj1a gpcr gpcrs gpr22 knock kupffer kv lefty1 lefty2 looping lpm lr master mesodermal morpholino organelles orphan patterning pitx2a player protrude randomization southpaw tem vesicle	243r abrogated adenovirus antagonizes cooperative disrupt e1a eh1 electrophoretic exerted implying kannabiran labrie mathews morris mutational nucleic oncoprotein p107 pcna proliferating relieves repress res retain suggestive transactivating unable virol
Tagcloud (Intersection) ?