PLEKHA2 and MPDZ

Number of citations of the paper that reports this interaction (PMID 11802782)
18

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		PLEKHA2	MPDZ
Gene Name		pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	multiple PDZ domain protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane Protein Complex	Cytoplasm Tight Junction Postsynaptic Density Apical Plasma Membrane Apicolateral Plasma Membrane Dendrite Cytoplasmic Vesicle Schmidt-Lanterman Incisure Postsynaptic Membrane
	Molecular Function	Fibronectin Binding Protein Binding Lipid Binding Laminin Binding	Protein Binding Protein C-terminus Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion	Cell Adhesion Viral Process Myelination
Pathways
Drugs
Diseases
GWAS			Corneal structure ( 23291589)
Protein-Protein Interactions		2 interactors: MPDZ PLEKHA1	13 interactors: ABCA1 CAMK2A CLDN1 CLDN5 CSPG4 DRD3 F11R HTR2C KIT PLEKHA1 PLEKHA2 RNF5 SYNGAP1
Entrez ID		59339	8777
HPRD ID			09155
Ensembl ID		ENSG00000169499	ENSG00000107186
Uniprot IDs		A8K727 Q9HB19	F5H1U9 O75970
PDB IDs			2FCF 2FNE 2IWN 2IWO 2IWP 2IWQ 2O2T 2OPG 2QG1
Enriched GO Terms of Interacting Partners?		Luteinization Leydig Cell Differentiation Phosphatidylinositol 3-kinase Signaling Estrogen Metabolic Process Face Morphogenesis Ruffle Organization Androgen Metabolic Process Negative Regulation Of Protein Kinase B Signaling B Cell Receptor Signaling Pathway Head Morphogenesis Platelet-derived Growth Factor Receptor Signaling Pathway Face Development Body Morphogenesis Cellular Response To Hydrogen Peroxide Ovulation Cycle Process Cellular Response To Reactive Oxygen Species Palate Development Female Gonad Development Multicellular Organism Growth Ovulation Cycle Development Of Primary Female Sexual Characteristics Regulation Of Protein Kinase B Signaling Response To Hydrogen Peroxide Antigen Receptor-mediated Signaling Pathway Phosphatidylinositol-mediated Signaling Post-embryonic Development Myelination Axon Ensheathment Male Gonad Development	Regulation Of Intracellular Signal Transduction Regulation Of Neuronal Synaptic Plasticity Regulation Of Signaling Visual Learning Visual Behavior Associative Learning Regulation Of Synaptic Transmission Regulation Of Signal Transduction Learning Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Response To Radiation Single-organism Behavior Regulation Of Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Membrane Permeability Response To Abiotic Stimulus Negative Regulation Of Protein Kinase B Signaling Behavior Regulation Of MAPK Cascade Cellular Response To Stimulus Signal Transduction Learning Or Memory Cognition Negative Regulation Of Cell Differentiation Regulation Of Lipid Metabolic Process Homeostatic Process Rhythmic Process Mast Cell Cytokine Production Melanocyte Adhesion Dendritic Cell Cytokine Production Mast Cell Proliferation Signaling Response To Light Stimulus Cell Communication Membrane Organization Chemical Homeostasis Positive Regulation Of Metabolic Process Cellular Localization Response To Stress Regulation Of Cell Differentiation Regulation Of CAMP Biosynthetic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Sodium:proton Antiporter Activity Regulation Of Corticotropin-releasing Hormone Secretion Gastric Emptying Kit Signaling Pathway Erythropoietin-mediated Signaling Pathway Phospholipase C-activating Serotonin Receptor Signaling Pathway
Tagcloud ?			a4 ace2 affective affectivity bonferroni combine converting correction endoperoxide exceeded gated nociceptive nonspecific oppera orofacial phenotypes prostaglandin ptgs1 rs10809907 rs1514280 rs3842803 rs466448 rs6432860 scn1a summation temporomandibular thresholds tmd
Tagcloud (Difference) ?			a4 ace2 affective affectivity bonferroni combine converting correction endoperoxide exceeded gated nociceptive nonspecific oppera orofacial phenotypes prostaglandin ptgs1 rs10809907 rs1514280 rs3842803 rs466448 rs6432860 scn1a summation temporomandibular thresholds tmd
Tagcloud (Intersection) ?