PLEKHA2 and GIPC3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLEKHA2	GIPC3
Description		pleckstrin homology domain containing A2	GIPC PDZ domain containing family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane Protein-containing Complex
	Molecular Function	Fibronectin Binding Protein Binding Phospholipid Binding Lipid Binding PDZ Domain Binding Laminin Binding Phosphatidylinositol-3,4-bisphosphate Binding	Protein Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion
Pathways		Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		High density lipoprotein cholesterol levels ( 31211820) Monocyte percentage of white cells ( 32888494)
Interacting Genes		19 interacting genes: COG6 DLG2 DLG3 EGLN3 FHL5 GIPC1 GIPC2 GIPC3 GOLGA2 HSF2BP KANK2 LNX1 M1AP MPDZ PLEKHA1 PTPN13 SNTG1 TEPSIN TRIM23	3 interacting genes: FZD3 PLEKHA2 ST6GAL2
Entrez ID		59339	126326
HPRD ID			16386
Ensembl ID		ENSG00000169499	ENSG00000179855
Uniprot IDs		A0A087WZ32 Q9HB19	A0A2R8Y651 Q8TF64
PDB IDs
Enriched GO Terms of Interacting Partners?			PDZ Domain Binding Serotonergic Neuron Axon Guidance Dopaminergic Neuron Axon Guidance Negative Regulation Of Mitotic Cell Cycle, Embryonic Midbrain Morphogenesis Beta-galactoside Alpha-2,6-sialyltransferase Activity Regulation Of Mitotic Cell Cycle, Embryonic Cell Proliferation In Midbrain Negative Regulation Of Execution Phase Of Apoptosis Sympathetic Ganglion Development Sialylation Filopodium Tip Wnt Receptor Activity Ganglion Development Commissural Neuron Axon Guidance Motor Neuron Migration Sialyltransferase Activity Post-anal Tail Morphogenesis Establishment Of Planar Polarity Laminin Binding Positive Regulation Of Neuroblast Proliferation Presynaptic Active Zone Membrane Wnt-protein Binding Phosphatidylinositol-3,4-bisphosphate Binding Fibronectin Binding Midbrain Development Wnt Signaling Pathway, Planar Cell Polarity Pathway Response To Electrical Stimulus Presynaptic Active Zone Hair Follicle Development Regulation Of Neuroblast Proliferation Non-canonical Wnt Signaling Pathway Positive Regulation Of Neural Precursor Cell Proliferation Oligosaccharide Metabolic Process Inner Ear Morphogenesis Positive Regulation Of Cell-matrix Adhesion Lateral Plasma Membrane Golgi Cisterna Membrane Hair Cycle Process
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