PLEKHA2 and PLEKHA1

Number of citations of the paper that reports this interaction (PMID 11802782)
18

Data Source:
BioGRID (two hybrid)

		PLEKHA2	PLEKHA1
Gene Name		pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane Protein Complex	Nucleoplasm Cytoplasm Plasma Membrane Ruffle Membrane Extracellular Vesicular Exosome
	Molecular Function	Fibronectin Binding Protein Binding Lipid Binding Laminin Binding	Protein Binding PDZ Domain Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Positive Regulation Of Cell-matrix Adhesion	Luteinization Spermatogenesis Androgen Metabolic Process Estrogen Metabolic Process Post-embryonic Development Phosphatidylinositol 3-kinase Signaling Ruffle Organization Leydig Cell Differentiation Multicellular Organism Growth Establishment Of Protein Localization Platelet-derived Growth Factor Receptor Signaling Pathway Skeletal System Morphogenesis B Cell Receptor Signaling Pathway Negative Regulation Of Protein Kinase B Signaling Palate Development Face Morphogenesis Cellular Response To Hydrogen Peroxide
Pathways
Drugs
Diseases
GWAS			Age-related macular degeneration ( 23577725 23536807) Age-related macular degeneration (extreme sampling) ( 23577725) Height ( 20189936)
Protein-Protein Interactions		2 interactors: MPDZ PLEKHA1	5 interactors: CRKL MPDZ PLEKHA2 PTPN13 SH3BP4
Entrez ID		59339	59338
HPRD ID			09686
Ensembl ID		ENSG00000169499	ENSG00000107679
Uniprot IDs		A8K727 Q9HB19	B3KQL5 Q5RGS4 Q9HB21
PDB IDs			1EAZ
Enriched GO Terms of Interacting Partners?		Luteinization Leydig Cell Differentiation Phosphatidylinositol 3-kinase Signaling Estrogen Metabolic Process Face Morphogenesis Ruffle Organization Androgen Metabolic Process Negative Regulation Of Protein Kinase B Signaling B Cell Receptor Signaling Pathway Head Morphogenesis Platelet-derived Growth Factor Receptor Signaling Pathway Face Development Body Morphogenesis Cellular Response To Hydrogen Peroxide Ovulation Cycle Process Cellular Response To Reactive Oxygen Species Palate Development Female Gonad Development Multicellular Organism Growth Ovulation Cycle Development Of Primary Female Sexual Characteristics Regulation Of Protein Kinase B Signaling Response To Hydrogen Peroxide Antigen Receptor-mediated Signaling Pathway Phosphatidylinositol-mediated Signaling Post-embryonic Development Myelination Axon Ensheathment Male Gonad Development
Tagcloud ?			abundantly adulthood became belongs contains conversion cytosol dominance dominancy e13 e17 encodes exons gradually homology maintaining overlay p2 phosphoinositides pi3p pi4p pi5p pleckstrin splicing trp ubiquitously ww
Tagcloud (Difference) ?			abundantly adulthood became belongs contains conversion cytosol dominance dominancy e13 e17 encodes exons gradually homology maintaining overlay p2 phosphoinositides pi3p pi4p pi5p pleckstrin splicing trp ubiquitously ww
Tagcloud (Intersection) ?