PLEKHA1

Gene Name		pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Plasma Membrane Ruffle Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding PDZ Domain Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Luteinization Spermatogenesis Androgen Metabolic Process Estrogen Metabolic Process Post-embryonic Development Phosphatidylinositol 3-kinase Signaling Ruffle Organization Leydig Cell Differentiation Multicellular Organism Growth Establishment Of Protein Localization Platelet-derived Growth Factor Receptor Signaling Pathway Skeletal System Morphogenesis B Cell Receptor Signaling Pathway Negative Regulation Of Protein Kinase B Signaling Palate Development Face Morphogenesis Cellular Response To Hydrogen Peroxide
Pathways
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23577725 23536807) Age-related macular degeneration (extreme sampling) ( 23577725) Height ( 20189936)
Protein-protein Interactions		5 interactors: CRKL MPDZ PLEKHA2 PTPN13 SH3BP4
Entrez ID		59338
HPRD ID		09686
Ensembl ID		ENSG00000107679
Uniprot IDs		B3KQL5 Q5RGS4 Q9HB21
PDB IDs		1EAZ
Enriched GO Terms of Interacting Partners?
Tagcloud ?		abundantly adulthood became belongs contains conversion cytosol dominance dominancy e13 e17 encodes exons gradually homology maintaining overlay p2 phosphoinositides pi3p pi4p pi5p pleckstrin splicing trp ubiquitously ww