UBL5 and FANCI

Number of citations of the paper that reports this interaction (PubMedID 25862789)
47

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		UBL5	FANCI
Description		ubiquitin like 5	FA complementation group I
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cajal Body	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Membrane DNA Repair Complex
	Molecular Function	Protein Binding Protein Tag Activity	DNA Binding Protein Binding DNA Polymerase Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Modification Process Positive Regulation Of Protein Targeting To Mitochondrion	DNA Repair DNA Damage Response Positive Regulation Of Protein Ubiquitination Interstrand Cross-link Repair
Pathways		mRNA Splicing - Major Pathway	Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
Drugs
Diseases			Fanconi anemia
GWAS		Sleep duration ( 30531941) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)	Height ( 25282103) Menopause (age at onset) ( 26414677) Red cell distribution width ( 32888494) Serum immune biomarker levels ( 32066700)
Interacting Genes		49 interacting genes: BEND7 BIN3 C1QTNF1 CCDC196 CCDC28B CERCAM CLK1 CLK2 CLK4 CTAG1A CTAG1B DMRTB1 FAM50B FANCI GCSAML HESX1 HID1 HMGXB4 HOXA1 HSPB2 KRTAP10-8 KRTAP13-3 LENG1 MBD3L1 NCOA5 NFYA NME4 NRIP3 PAX4 PHACTR3 PINX1 PRMT8 PSME2 SART1 SEPTIN2 SERTAD3 SF1 SMCP SPANXB1 SPATC1L TEX35 THAP3 TLE5 TRIM27 TRIM39 WASHC1 ZFP41 ZNF124 ZNF618	13 interacting genes: AKT1 APP ATR BRCA2 CEBPA FANCD2 FANCL MTDH MTNR1B PIAS1 RAD51 UBL5 USP1
Entrez ID		59286	55215
HPRD ID		06028	13339
Ensembl ID		ENSG00000198258	ENSG00000140525
Uniprot IDs		A0A024R7B0 Q9BZL1	A0A6Q8PGF4 A0A8Q3SIW9 B3KNW8 Q9NVI1
PDB IDs		1P0R 4PYU 6AHD 7AAV 7ABF 7ABG 7ABI 8H6K 8Q7N 8QO9	6VAA 6VAD 6VAE 6VAF 7AY1 7ZF1 8A9J 8A9K
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Serine/threonine/tyrosine Kinase Activity	Response To Radiation Interstrand Cross-link Repair DNA Repair Response To Light Stimulus Response To Gamma Radiation Nucleic Acid Metabolic Process Cellular Response To Stress DNA Metabolic Process Double-strand Break Repair DNA Damage Response Mitotic Recombination-dependent Replication Fork Processing Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Stress Response To Ionizing Radiation Replication Fork Processing Regulation Of Cell Cycle Response To UV Response To Stress Nuclear Ubiquitin Ligase Complex Regulation Of Cell Cycle Phase Transition Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Reproductive Process Cellular Response To Ionizing Radiation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Mitotic Cell Cycle Double-strand Break Repair Involved In Meiotic Recombination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Catabolic Process Macromolecule Metabolic Process Lateral Element Telomere Maintenance Via Recombination DNA Repair Complex Telomere Maintenance Nucleoplasm Regulation Of Signal Transduction Nucleus Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process PML Body Positive Regulation Of Proteasomal Protein Catabolic Process Mitotic Recombination Chromosome Organization Telomere Organization Positive Regulation Of Mitotic Cell Cycle Signal Transduction DNA Polymerase Binding Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Cell Cycle Process
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