FANCI

Description		FA complementation group I
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Membrane DNA Repair Complex
	Molecular Function	DNA Binding Protein Binding DNA Polymerase Binding
	Biological Process	DNA Repair DNA Damage Response Positive Regulation Of Protein Ubiquitination Interstrand Cross-link Repair
Pathways		Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
Drugs
Diseases		Fanconi anemia
GWAS		Height ( 25282103) Menopause (age at onset) ( 26414677) Red cell distribution width ( 32888494) Serum immune biomarker levels ( 32066700)
Interacting Genes		13 interacting genes: AKT1 APP ATR BRCA2 CEBPA FANCD2 FANCL MTDH MTNR1B PIAS1 RAD51 UBL5 USP1
Entrez ID		55215
HPRD ID		13339
Ensembl ID		ENSG00000140525
Uniprot IDs		A0A6Q8PGF4 A0A8Q3SIW9 B3KNW8 Q9NVI1
PDB IDs		6VAA 6VAD 6VAE 6VAF 7AY1 7ZF1 8A9J 8A9K
Enriched GO Terms of Interacting Partners?		Response To Radiation Interstrand Cross-link Repair DNA Repair Response To Light Stimulus Response To Gamma Radiation Nucleic Acid Metabolic Process Cellular Response To Stress DNA Metabolic Process Double-strand Break Repair DNA Damage Response Mitotic Recombination-dependent Replication Fork Processing Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Stress Response To Ionizing Radiation Replication Fork Processing Regulation Of Cell Cycle Response To UV Response To Stress Nuclear Ubiquitin Ligase Complex Regulation Of Cell Cycle Phase Transition Positive Regulation Of Proteolysis Positive Regulation Of Protein Catabolic Process Reproductive Process Cellular Response To Ionizing Radiation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Mitotic Cell Cycle Double-strand Break Repair Involved In Meiotic Recombination Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Catabolic Process Macromolecule Metabolic Process Lateral Element Telomere Maintenance Via Recombination DNA Repair Complex Telomere Maintenance Nucleoplasm Regulation Of Signal Transduction Nucleus Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process PML Body Positive Regulation Of Proteasomal Protein Catabolic Process Mitotic Recombination Chromosome Organization Telomere Organization Positive Regulation Of Mitotic Cell Cycle Signal Transduction DNA Polymerase Binding Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Protein Catabolic Process Regulation Of Cell Cycle Process
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