OVOL2 and ZNF526

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		OVOL2	ZNF526
Description		ovo like zinc finger 2	zinc finger protein 526
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Neural Crest Cell Migration Neural Fold Formation Heart Looping Regulation Of Transcription By RNA Polymerase II Heart Development Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Epidermis Development Epidermal Cell Differentiation Dorsal/ventral Pattern Formation Negative Regulation Of Signal Transduction Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Keratinocyte Proliferation Negative Regulation Of Transcription By Competitive Promoter Binding Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Cell Differentiation Regulation Of Keratinocyte Differentiation Negative Regulation Of Keratinocyte Differentiation Positive Regulation Of Keratinocyte Differentiation Negative Regulation Of Notch Signaling Pathway Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Embryonic Digestive Tract Morphogenesis Negative Regulation Of Multicellular Organismal Process Regulation Of Cell Cycle Endocardium Formation Heart Trabecula Formation Negative Regulation Of SMAD Protein Signal Transduction Labyrinthine Layer Blood Vessel Development White Fat Cell Proliferation Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of Stem Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Low density lipoprotein cholesterol levels ( 32154731) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Nicotine dependence symptom count ( 25555482) Red blood cell count ( 32888494)	Hodgkin's lymphoma ( 34216518) Meat-related diet ( 32066663)
Interacting Genes		5 interacting genes: MDM2 NCOR1 PARP1 RELA ZNF526	54 interacting genes: ATXN7L2 BAHD1 C8orf33 FAM161A FAM90A1 FARS2 GPATCH2L GRAP2 HNRNPK IL16 INO80B IQUB KAT5 LMO1 LMO3 MAPRE3 MRPL11 NCK2 NME7 OVOL2 PADI6 PBK PHF1 PIN1 PRKAB2 PRPF18 RBM10 SCNM1 SEPHS1 SPANXN2 SYCE1L TCEA2 THAP1 THAP12 TRIM41 U2AF2 VCX2 YJU2 ZBTB24 ZFP91 ZNF124 ZNF264 ZNF408 ZNF438 ZNF497 ZNF524 ZNF575 ZNF578 ZNF696 ZNF76 ZNF774 ZNF792 ZNF835 ZNF837
Entrez ID		58495	116115
HPRD ID		15780	15818
Ensembl ID		ENSG00000125850	ENSG00000167625
Uniprot IDs		Q9BRP0	H9ZYJ3 Q8TF50
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To UV Cellular Response To Oxidative Stress Negative Regulation Of ATP Metabolic Process Histone Deacetylase Binding Response To Steroid Hormone Cellular Response To Peptide Hormone Stimulus Negative Regulation Of MiRNA Transcription Negative Regulation Of Intracellular Signal Transduction Signal Transduction Involved In Regulation Of Gene Expression Cellular Response To Chemical Stress Response To Alcohol Cellular Response To Growth Factor Stimulus Ubiquitin Protein Ligase Binding Response To Peptide Hormone Response To Light Stimulus Response To Growth Factor Negative Regulation Of Transcription By RNA Polymerase II Response To Gamma Radiation Cellular Response To Hormone Stimulus Response To Oxidative Stress Regulation Of ATP Metabolic Process NAD+-histone H3S10 Serine ADP-ribosyltransferase Activity Enzyme Binding Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway NAD+-histone H2BS6 Serine ADP-ribosyltransferase Activity Regulation Of Purine Nucleotide Metabolic Process Protein Kinase Binding NAD+-histone H2BE35 Glutamate ADP-ribosyltransferase Activity Regulation Of Apoptotic Signaling Pathway NAD+-protein-histidine ADP-ribosyltransferase Activity Response To Radiation NAD+-protein-tyrosine ADP-ribosyltransferase Activity Transcription Repressor Complex Response To Vitamin Response To Formaldehyde Cellular Response To Vitamin B1 Cellular Response To Hydrogen Peroxide Regulation Of MiRNA Transcription Cellular Response To UV Response To Alkaloid Regulation Of MiRNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To Hydrogen Peroxide Cellular Response To Light Stimulus Negative Regulation Of Signal Transduction Negative Regulation Of RNA Metabolic Process Cellular Response To Reactive Oxygen Species Positive Regulation Of Myofibroblast Differentiation NAD+-protein-serine ADP-ribosyltransferase Activity	Zinc Ion Binding Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Metal Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Spliceosomal Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing
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