ZNF71 and SART3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF71	SART3
Description		zinc finger protein 71	spliceosome associated factor 3, U4/U6 recycling protein
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm U6atac SnRNP Cytoplasm Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex ASAP Complex U4/U6 SnRNP U4atac/U6atac SnRNP
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleic Acid Binding RNA Binding Protein Binding U6 SnRNA Binding U4 SnRNA Binding U6atac SnRNA Binding Protein-macromolecule Adaptor Activity Histone Binding Ubiquitin-specific Protease Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Cell Morphogenesis Nucleosome Assembly RNA Processing MRNA Processing RNA Splicing Regulation Of Gene Expression Homeostasis Of Number Of Cells Regulation Of RNA Metabolic Process Hematopoietic Stem Cell Proliferation Transcription Elongation-coupled Chromatin Remodeling
Pathways		Generic Transcription Pathway
Drugs
Diseases			Disseminated superficial actinic porokeratosis (DSAP)
GWAS		IgE levels in asthmatics ( 23967269) Lymphocyte count ( 32888494) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Acne (severe) ( 24927181)
Interacting Genes		26 interacting genes: BYSL CSNK2B DVL3 FXR1 KDM1A LGALS14 MFAP1 PGRMC1 PHF1 PICK1 PLK1 PRKCZ PRPF31 RIN3 SART3 SSX2IP TRIM41 U2AF2 ZBTB9 ZGPAT ZNF417 ZNF497 ZNF524 ZNF648 ZNF792 ZNF835	29 interacting genes: AR C6 COIL CTBP1 H2AC20 H2BC21 MEGF10 MIR1-1 MIR128-2 MIR143 MIR18A MIR18B MIR19B2 MIR200B MIR200C MIR221 MIR34A MIR34B MIR7-1 MIR7-3 MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 PRPF3 RNF10 RNPS1 ZNF620 ZNF71
Entrez ID		58491	9733
HPRD ID		11838	11532
Ensembl ID		ENSG00000197951	ENSG00000075856
Uniprot IDs		M0R0C0 Q9NQZ8	A0A499FI31 Q15020
PDB IDs			2DO4 5CTQ 5CTR 5CTT 5JJW 5JJX 5JPZ 7XX8 7XX9
Enriched GO Terms of Interacting Partners?		Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Zinc Ion Binding U4 SnRNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Metal Ion Binding Regulation Of Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Macromolecule Biosynthetic Process Spliceosomal Tri-snRNP Complex Assembly Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cellular Component Organization DNA Repair-dependent Chromatin Remodeling Identical Protein Binding U2-type Spliceosomal Complex	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process MRNA Destabilization Negative Regulation Of Metabolic Process RNA Destabilization Positive Regulation Of MRNA Catabolic Process MRNA 3'-UTR Binding Positive Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Stability Regulation Of Sprouting Angiogenesis Regulation Of RNA Stability Regulation Of MRNA Metabolic Process Negative Regulation Of Sprouting Angiogenesis Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Macromolecule Metabolic Process Regulation Of Muscle Cell Differentiation Regulation Of Angiogenesis Regulation Of Smooth Muscle Cell Differentiation Regulation Of Vasculature Development Regulation Of Metabolic Process Negative Regulation Of Transmembrane Transport Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Multicellular Organismal Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Cell Population Proliferation Negative Regulation Of Interleukin-33 Production Positive Regulation Of Tissue Remodeling Positive Regulation Of Smooth Muscle Cell Differentiation Negative Regulation Of Signal Transduction Extracellular Vesicle Negative Regulation Of Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane Negative Regulation Of Response To Drug Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Developmental Process Negative Regulation Of Cytokine Production Regulation Of Endothelial Cell Migration
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