ZNF71 and ZNF497

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF71	ZNF497
Description		zinc finger protein 71	zinc finger protein 497
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		IgE levels in asthmatics ( 23967269) Lymphocyte count ( 32888494) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		26 interacting genes: BYSL CSNK2B DVL3 FXR1 KDM1A LGALS14 MFAP1 PGRMC1 PHF1 PICK1 PLK1 PRKCZ PRPF31 RIN3 SART3 SSX2IP TRIM41 U2AF2 ZBTB9 ZGPAT ZNF417 ZNF497 ZNF524 ZNF648 ZNF792 ZNF835	39 interacting genes: CCDC136 CYSRT1 DVL3 GGA3 GOLGA6L9 HOOK2 KHDRBS2 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP4-12 KRTAP4-4 KRTAP6-3 KRTAP9-3 MCC MDFI MID2 MTUS2 NBPF19 NOTCH2NLA OSBPL3 PICK1 PTPN21 PURB SULT2B1 TNS2 TRIM41 VWC2 ZBTB8A ZNF473 ZNF526 ZNF71 ZNF792 ZNF835 ZNF837 ZRANB1
Entrez ID		58491	162968
HPRD ID		11838	15806
Ensembl ID		ENSG00000197951	ENSG00000174586
Uniprot IDs		M0R0C0 Q9NQZ8	Q6ZNH5
PDB IDs
Enriched GO Terms of Interacting Partners?		Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Zinc Ion Binding U4 SnRNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Metal Ion Binding Regulation Of Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Macromolecule Biosynthetic Process Spliceosomal Tri-snRNP Complex Assembly Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cellular Component Organization DNA Repair-dependent Chromatin Remodeling Identical Protein Binding U2-type Spliceosomal Complex	Intermediate Filament Keratin Filament
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