ZNF497 and KRTAP4-4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF497	KRTAP4-4
Description		zinc finger protein 497	keratin associated protein 4-4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription	Hair Cycle
Pathways			Keratinization
Drugs
Diseases
GWAS
Interacting Genes		39 interacting genes: CCDC136 CYSRT1 DVL3 GGA3 GOLGA6L9 HOOK2 KHDRBS2 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP4-12 KRTAP4-4 KRTAP6-3 KRTAP9-3 MCC MDFI MID2 MTUS2 NBPF19 NOTCH2NLA OSBPL3 PICK1 PTPN21 PURB SULT2B1 TNS2 TRIM41 VWC2 ZBTB8A ZNF473 ZNF526 ZNF71 ZNF792 ZNF835 ZNF837 ZRANB1	80 interacting genes: ADAMTSL4 ALX1 AQP1 BAG4 CATSPER1 CBX2 CRCT1 CREB5 CYSRT1 GLRX3 GNE HEY2 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-3 KRTAP13-2 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-2 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP6-3 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A MEOX2 NBPF19 NOTCH2NLA NPDC1 NR4A3 NUFIP2 OTX1 POU4F2 SHFL SMCP TNS2 TRIM42 VASN ZNF440 ZNF497 ZNF764
Entrez ID		162968	84616
HPRD ID		15806	13945
Ensembl ID		ENSG00000174586	ENSG00000171396
Uniprot IDs		Q6ZNH5	Q9BYR3
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament	Intermediate Filament Keratin Filament Keratinization Epidermis Development Tissue Development Identical Protein Binding Hair Cycle Protein Binding Cytosol Mesenchymal Cell Development
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