ZNF497 and ZNF473

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZNF497	ZNF473
Description		zinc finger protein 497	zinc finger protein 473
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cajal Body
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II MRNA 3'-end Processing By Stem-loop Binding And Cleavage
Pathways			SLBP independent Processing of Histone Pre-mRNAs Generic Transcription Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS
Interacting Genes		39 interacting genes: CCDC136 CYSRT1 DVL3 GGA3 GOLGA6L9 HOOK2 KHDRBS2 KRTAP1-1 KRTAP1-3 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP4-12 KRTAP4-4 KRTAP6-3 KRTAP9-3 MCC MDFI MID2 MTUS2 NBPF19 NOTCH2NLA OSBPL3 PICK1 PTPN21 PURB SULT2B1 TNS2 TRIM41 VWC2 ZBTB8A ZNF473 ZNF526 ZNF71 ZNF792 ZNF835 ZNF837 ZRANB1	22 interacting genes: AEN APP CLK2 CLK3 DHX57 GPATCH2L KRTAP10-10 KRTAP10-8 KRTAP10-9 LSM11 PRPF31 RBM10 RNPS1 SLBP TRIM41 ZNF202 ZNF250 ZNF408 ZNF497 ZNF792 ZNF837 ZSCAN12
Entrez ID		162968	25888
HPRD ID		15806	11721
Ensembl ID		ENSG00000174586	ENSG00000142528
Uniprot IDs		Q6ZNH5	B4DY71 F8WEC7 Q8WTR7
PDB IDs			2EMB 2EMC 2EME 2EOU 2EOX 2EOY 2EOZ 2YRH 2YRJ 2YSV 2YTD 2YTE 2YTT 2YU5 9AZI
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament	Identical Protein Binding PTB Domain Binding Nucleus MRNA 3'-end Processing By Stem-loop Binding And Cleavage Histone Pre-mRNA 3'end Processing Complex Regulation Of RNA Splicing Zinc Ion Binding Nuclear Speck RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding MRNA Processing Keratin Filament Negative Regulation Of MRNA Splicing, Via Spliceosome Histone MRNA Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Gene Expression Positive Regulation Of Toll Signaling Pathway Protein Serine/threonine/tyrosine Kinase Activity RNA Processing MRNA 3'-end Processing MRNA Metabolic Process Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Ribosomal Large Subunit Export From Nucleus Negative Regulation Of RNA Splicing Ribonucleoprotein Complex Localization Intermediate Filament Ribonucleoprotein Complex
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