NEMP1 and GUCA2A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NEMP1	GUCA2A
Description		nuclear envelope integral membrane protein 1	guanylate cyclase activator 2A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Membrane	Extracellular Region
	Molecular Function	Protein Binding	Hormone Activity Protein Binding Guanylate Cyclase Activator Activity
	Biological Process	Erythrocyte Enucleation Erythrocyte Maturation Nuclear Membrane Organization	Signal Transduction
Pathways			Digestion
Drugs
Diseases
GWAS		Asthma ( 31959851)
Interacting Genes		31 interacting genes: ADIPOQ AQP10 ASGR1 BRICD5 C3orf52 C5 CD81 CLEC7A CLRN2 CNIH3 COL4A5 CXCL16 CXCL9 FAXDC2 GPR108 GUCA2A INSIG2 PNLIPRP1 RTP2 SCARF1 SERP2 STX12 TMEM14A TMEM229B TMEM42 TMEM86B TMEM97 TMUB2 TSPAN33 UPK1B VAMP3	15 interacting genes: ASPH FFAR2 GJA8 GOLM1 GUCY2C NEMP1 SGTA SLC34A2 TMEM179B TMEM237 TMEM31 TMEM86B TRAM1 UBQLN1 UBQLN2
Entrez ID		23306	2980
HPRD ID		13793	00767
Ensembl ID		ENSG00000166881	ENSG00000197273
Uniprot IDs		O14524	Q02747
PDB IDs			1GNA 1GNB 1O8R
Enriched GO Terms of Interacting Partners?		Membrane Protein Localization To Cell Periphery Localization Within Membrane Chemokine Activity Tetraspanin-enriched Microdomain Receptor-mediated Endocytosis Positive Regulation Of Chemokine Production Protein Localization To Membrane Positive Regulation Of Monocyte Chemotactic Protein-1 Production Oxysterol Binding Protein Localization To Plasma Membrane	Membrane Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteolysis Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Proteolysis Protein Insertion Into ER Membrane Polyubiquitin Modification-dependent Protein Binding Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Store-operated Calcium Channel Activity D-lysine 5,6-aminomutase Activity Response To Endoplasmic Reticulum Stress Peptidyl-aspartic Acid 3-dioxygenase Activity Plasma Membrane Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Protein Targeting To Membrane TRC Complex Protein Insertion Into Membrane Negative Regulation Of G Protein-coupled Receptor Internalization Ether Hydrolase Activity Alkenylglycerophosphocholine Hydrolase Activity Regulation Of Transmembrane Transporter Activity Regulation Of Monoatomic Ion Transmembrane Transporter Activity Autophagosome Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Autophagosome Assembly
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