CXCR6 and CXCL16

Number of citations of the paper that reports this interaction (PMID 11017100)
93

Data Source:
HPRD (in vitro, in vivo)

		CXCR6	CXCL16
Gene Name		chemokine (C-X-C motif) receptor 6	chemokine (C-X-C motif) ligand 16
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Extracellular Space Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	G-protein Coupled Receptor Activity Coreceptor Activity C-X-C Chemokine Receptor Activity	Low-density Lipoprotein Receptor Activity Scavenger Receptor Activity Chemokine Activity
	Biological Process	Chemotaxis Inflammatory Response G-protein Coupled Receptor Signaling Pathway Viral Genome Replication Chemokine-mediated Signaling Pathway	Receptor-mediated Endocytosis Chemotaxis T Cell Chemotaxis Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Response To Cytokine Response To Interferon-gamma Response To Tumor Necrosis Factor Cellular Response To Lipopolysaccharide
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: CXCL16	13 interactors: ADAMTSL4 APP CCDC155 CXCR6 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP5-9 MDFI MTUS2 NOTCH2NL TMEM239
Entrez ID		10663	58191
HPRD ID		05520	16103
Ensembl ID		ENSG00000172215	ENSG00000161921
Uniprot IDs		A0N0N3 O00574	Q9H2A7
PDB IDs
Enriched GO Terms of Interacting Partners?		T Cell Chemotaxis Lymphocyte Chemotaxis T Cell Migration Lymphocyte Migration Leukocyte Chemotaxis Positive Regulation Of Cell Growth Response To Tumor Necrosis Factor Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Cell Chemotaxis Response To Interferon-gamma Positive Regulation Of Growth Leukocyte Migration Response To Lipopolysaccharide Positive Regulation Of Cell Migration Response To Molecule Of Bacterial Origin Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Regulation Of Cell Growth Positive Regulation Of Locomotion Receptor-mediated Endocytosis Cellular Response To Lipid
Tagcloud ?		apposed attack borrelia burgdorferi caught cd1d disk dissemination encompass explains extravascular fail glycolipids granzyme homing inkt intravital invariant joint joints killer lyme microbe microbes multichannel patrolling penetrance spinning vasculature	aaa aaas adventitial aneurysms aorta arteries atherosclerosis atherothrombosis atherothrombotic ccl19 ccl20 ccl21 chemokine chemokines chemotaxis conditioned contributors converted cryosections evolutive immunofluorescence medium qpcr sma smcs tertiary tlos trigger
Tagcloud (Difference) ?		apposed attack borrelia burgdorferi caught cd1d disk dissemination encompass explains extravascular fail glycolipids granzyme homing inkt intravital invariant joint joints killer lyme microbe microbes multichannel patrolling penetrance spinning vasculature	aaa aaas adventitial aneurysms aorta arteries atherosclerosis atherothrombosis atherothrombotic ccl19 ccl20 ccl21 chemokine chemokines chemotaxis conditioned contributors converted cryosections evolutive immunofluorescence medium qpcr sma smcs tertiary tlos trigger
Tagcloud (Intersection) ?