PTS and COIL

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PTS	COIL
Gene Name		6-pyruvoyltetrahydropterin synthase	coilin
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol	Nucleus Nucleoplasm Nucleolus Cytoplasm Cajal Body Membrane
	Molecular Function	6-pyruvoyltetrahydropterin Synthase Activity Identical Protein Binding Protein Homodimerization Activity Metal Ion Binding	Protein Binding Protein C-terminus Binding Identical Protein Binding
	Biological Process	Cellular Amino Acid Metabolic Process Tetrahydrobiopterin Biosynthetic Process Central Nervous System Development Small Molecule Metabolic Process Nitric Oxide Metabolic Process Regulation Of Nitric-oxide Synthase Activity
Pathways		Metabolism of nitric oxide eNOS activation and regulation Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Drugs
Diseases
GWAS			Height ( 18391951)
Protein-Protein Interactions		12 interactors: ATM ATR COIL FNDC5 FXR2 LNX1 PBRM1 PRKDC PRKG2 SDCBP THAP10 WDYHV1	70 interactors: ACTN1 ACTN2 ACTN4 APP ARMCX1 ATXN1 ATXN1L BYSL C1QBP CCDC136 CCDC159 CCNE1 CDC23 CDK2 CEP70 CEP76 CSNK2B CYB5R2 DHX16 DNAJA3 DRG1 FGF12 FHL5 FXR2 GCC1 KALRN KAZN KLC2 KLC4 KLHL42 KLHL8 KPNA3 LNX1 MAD1L1 MFAP1 MYO5B NIF3L1 NOLC1 NUDT18 PDE4D PDLIM5 PIAS4 PICK1 PLEKHG4 POLR2L PREPL PRMT1 PRMT8 PSMA1 PSME3 PTS SART3 SCYL1 SMN1 SNRPB SNRPF SNX6 TAF9 TCAF1 TCEB3B TFCP2 TGS1 TSPYL2 WDR34 WDYHV1 XRCC5 XRCC6 ZBTB25 ZCCHC10 ZNF277
Entrez ID		5805	8161
HPRD ID		11840	02605
Ensembl ID		ENSG00000150787	ENSG00000121058
Uniprot IDs		Q03393	P38432
PDB IDs		3I2B
Enriched GO Terms of Interacting Partners?		Peptidyl-serine Phosphorylation Response To Gamma Radiation Double-strand Break Repair Via Homologous Recombination Recombinational Repair Replicative Senescence Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Signal Transduction By P53 Class Mediator Response To Ionizing Radiation DNA Damage Checkpoint Double-strand Break Repair Cellular Response To Gamma Radiation V(D)J Recombination Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cellular Response To Heat Protein Autophosphorylation Cell Cycle Checkpoint DNA Recombination Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Cellular Protein Metabolic Process Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Cellular Response To Ionizing Radiation Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Cellular Response To Heat Negative Regulation Of Protein Metabolic Process Positive Regulation Of Response To DNA Damage Stimulus Cell Aging Telomere Maintenance Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Peptidyl-amino Acid Modification Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Somitogenesis Cell Cycle Process Signal Transduction In Response To DNA Damage Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Response To Radiation Somite Development Mitotic DNA Damage Checkpoint Cellular Protein Modification Process Mitotic DNA Integrity Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle B Cell Differentiation Response To Heat Segmentation Heart Development Regulation Of Response To DNA Damage Stimulus Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition	Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Spliceosomal SnRNP Assembly Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Regulation Of Metabolic Process MRNA Processing Ribonucleoprotein Complex Biogenesis RNA Processing Regulation Of Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Mitotic Cell Cycle RNA Splicing Gene Expression Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Ribonucleoprotein Complex Assembly Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Hyperosmotic Salinity Response Protein Localization To Tight Junction Regulation Of Cellular Protein Metabolic Process Mitotic Cell Cycle Process Regulation Of RNA Metabolic Process MRNA Metabolic Process Transcription, DNA-templated Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition RNA Biosynthetic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Process Regulation Of Protein Metabolic Process Platelet Degranulation Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecular Complex Assembly Negative Regulation Of Cellular Protein Metabolic Process Mitotic Cell Cycle Checkpoint DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Gene Expression Cellular Response To X-ray Regulation Of Ubiquitin-protein Transferase Activity Viral Process Cellular Component Assembly
Tagcloud ?		achieve aida apl atra became chemotherapy consolidation converting courses cytogenetic fab gimema hematologic interpretation lap0493 m3 majority molecularly morphologic mths myelogenous persistence promyelocytic q12 q22 remission successive transcript validity	augment augments bait cbp coactivator coiled enhances except hybrid ifngamma instead interactor interacts interestingly intrinsic lacks myc nmi potentiate recruitment reveal screen stat stat1 stat2 stat5 stat5b stats yeast
Tagcloud (Difference) ?		achieve aida apl atra became chemotherapy consolidation converting courses cytogenetic fab gimema hematologic interpretation lap0493 m3 majority molecularly morphologic mths myelogenous persistence promyelocytic q12 q22 remission successive transcript validity	augment augments bait cbp coactivator coiled enhances except hybrid ifngamma instead interactor interacts interestingly intrinsic lacks myc nmi potentiate recruitment reveal screen stat stat1 stat2 stat5 stat5b stats yeast
Tagcloud (Intersection) ?