ADD2

Description		adducin 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane F-actin Capping Protein Complex Postsynaptic Density Membrane Cytoplasmic Vesicle Plasma Membrane Raft
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Calmodulin Binding Cytoskeletal Anchor Activity Protein Kinase Binding Spectrin Binding Protein Homodimerization Activity Protein Heterodimerization Activity Protein Dimerization Activity Actin Filament Binding
	Biological Process	Synapse Assembly Actin Cytoskeleton Organization Hemopoiesis Leukocyte Migration Leukocyte Tethering Or Rolling Barbed-end Actin Filament Capping Actin Filament Bundle Assembly Protein-containing Complex Assembly
Pathways		Miscellaneous transport and binding events
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Response to esketamine in treatment resistant depression ( 32724131)
Novel Interacting Genes		1 novel interacting genes: BRWD1
Interacting Genes		8 interacting genes: ADD1 APP CALM1 FYN PRKACA PRKCD PTPRZ1 RPH3A
Entrez ID		119
HPRD ID		00037
Ensembl ID		ENSG00000075340
Uniprot IDs		P35612 Q05DK5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transport Growth Factor Receptor Binding Plasma Membrane Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Establishment Of Protein Localization Regulation Of Calcium-mediated Signaling Regulation Of Dendritic Spine Maintenance Regulation Of Metal Ion Transport Regulation Of Biological Quality Regulation Of Superoxide Anion Generation Regulation Of Monoatomic Ion Transport Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Transport Positive Regulation Of Superoxide Anion Generation Positive Regulation Of Protein Localization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Regulation Of Protein Localization To Nucleus Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Fc Receptor Mediated Stimulatory Signaling Pathway Modulation Of Chemical Synaptic Transmission Calcium-mediated Signaling Calcium Channel Complex Cellular Response To Peptide Hormone Stimulus Ephrin Receptor Binding Regulation Of Establishment Of Protein Localization Regulation Of Superoxide Metabolic Process Regulation Of Multicellular Organismal Process Positive Regulation Of Cellular Component Organization Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Fc-gamma Receptor Signaling Pathway Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Motile Cilium Cell Projection Neuron Projection Organization Non-membrane Spanning Protein Tyrosine Kinase Activity Peptidyl-serine Phosphorylation Positive Regulation Of Protein Transport Membrane Regulation Of Neuron Apoptotic Process Regulation Of Blood Circulation Negative Regulation Of Actin Filament Polymerization Glutamate Receptor Signaling Pathway Learning Or Memory Perinuclear Region Of Cytoplasm Neuron Projection Morphogenesis Cellular Response To Amyloid-beta Sperm Midpiece Cell Projection Morphogenesis
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