GRHL2

Gene Name		grainyhead-like 2 (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cell-cell Junction
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	In Utero Embryonic Development Neural Tube Closure Cardiac Ventricle Morphogenesis Epithelial Cell Morphogenesis Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Cell Adhesion Brain Development Cell Proliferation Neural Tube Development Cell Junction Assembly Multicellular Organism Growth Embryonic Digit Morphogenesis Camera-type Eye Development Regulation Of DNA Methylation Embryonic Cranial Skeleton Morphogenesis Positive Regulation Of Telomerase Activity Face Development Lung Lobe Morphogenesis Lung Epithelial Cell Differentiation Tight Junction Assembly Epithelium Migration
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: APP GRHL3 LMO4
Entrez ID		79977
HPRD ID		10545
Ensembl ID		ENSG00000083307
Uniprot IDs		Q6ISB3
PDB IDs
Enriched GO Terms of Interacting Partners?		Central Nervous System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Synaptic Growth At Neuromuscular Junction Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Collateral Sprouting In Absence Of Injury Regulation Of Transcription From RNA Polymerase II Promoter Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Nervous System Development Anatomical Structure Morphogenesis Neuron Remodeling Positive Regulation Of Cellular Metabolic Process Morphogenesis Of An Epithelium Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Spinal Cord Association Neuron Differentiation Wound Healing Eyelid Development In Camera-type Eye Establishment Of Planar Polarity Organ Development Embryonic Morphogenesis Tissue Morphogenesis Cellular Copper Ion Homeostasis Regulation Of Cell Fate Specification Wnt Signaling Pathway, Planar Cell Polarity Pathway Ventral Spinal Cord Interneuron Differentiation RNA Metabolic Process Response To Wounding Copper Ion Homeostasis Suckling Behavior Dorsal Spinal Cord Development Morphogenesis Of A Polarized Epithelium Ectoderm Development Positive Regulation Of Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Cochlea Morphogenesis Gene Expression Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Non-canonical Wnt Signaling Pathway Transcription From RNA Polymerase II Promoter Mating Behavior Regulation Of Cell Fate Commitment Endoplasmic Reticulum Calcium Ion Homeostasis
Tagcloud ?		1192t 1445t autosomal consanguinity deafness disclosed dysphagia dystrophy ectodermal enamel exome grainyhead haploinsufficiency homozygous hyperpigmentation hypodontia hypoplasia ile482lys immortalized junctions keratoderma kuwaiti lifelong nail palmoplantar recessive sensorineural transcriptomic tyr398his