RBAK and CRACR2A

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		RBAK	CRACR2A
Name		RB associated KRAB zinc finger	calcium release activated channel regulator 2A
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Golgi Membrane Immunological Synapse Extracellular Region Cytoplasm Golgi Apparatus Microtubule Organizing Center Cytoskeleton Plasma Membrane Membrane Vesicle Trans-Golgi Network Membrane Weibel-Palade Body Specific Granule Lumen Specific Granule
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleotide Binding GTPase Activity G Protein Activity Calcium Ion Binding Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription	Store-operated Calcium Entry Adaptive Immune Response Immune System Process Monoatomic Ion Transport Calcium Ion Transport Intracellular Protein Localization Vesicle-mediated Transport Endosomal Transport Activation Of Store-operated Calcium Channel Activity Response To Histamine T-helper 1 Cell Differentiation Positive Regulation Of JNK Cascade Positive Regulation Of Calcium Ion Transport
Pathways		None	Neutrophil degranulation
GWAS		No GWAS studies recorded	Femur bone mineral density x serum urate levels interaction ( 34046847 ) Severe insulin-deficient type 2 diabetes ( 34737425 )
Interacting Genes		28 interacting genes: AQP1 AR BYSL CARD9 CIB3 CRACR2A DRC4 EFEMP2 EIF1AD FGF12 L3MBTL2 LMO4 LNX1 MAGOHB NEK6 PRKG1 PRPF31 RB1 SCNM1 SLC25A10 TCAF1 TNS2 TRIM41 TSGA10 TXK ZNF121 ZNF330 ZNF648	35 interacting genes: ANKRD29 ASB3 ATN1 CCHCR1 CDC23 DDIT3 FAM156A FAM156B FAM86C1P FKBP6 GIGYF1 GOLGA2 KRT31 KRT75 KRTAP13-1 KRTAP19-5 LRIF1 MDFI MID2 MKRN3 NOTCH2NLA OIP5 PNMA5 POLR1C RBAK RORB SLAIN1 SORBS3 TLE5 TRAF1 TRIM29 USP2 ZC2HC1C ZNF20 ZNF655
Entrez ID		57786	84766
HPRD ID		16296	10079
Ensembl ID		ENSG00000146587	ENSG00000130038
Uniprot IDs		Q9NYW8	Q9BSW2
PDB IDs		Not available	6PSD
GO Terms Enriched among Interactors		Positive Regulation Of Collagen Fibril Organization	Identical Protein Binding